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MABF311

Sigma-Aldrich

Anti-CD19 (mouse), PE, clone 6D5 Antibody

clone 6D5, from rat, PE

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别名:
B-lymphocyte antigen CD19, Differentiation antigen CD19, CD19
UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

rat

偶联物

PE

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

6D5, monoclonal

种属反应性

mouse

技术

flow cytometry: suitable

同位素/亚型

IgG2aκ

UniProt登记号

运输

wet ice

靶向翻译后修饰

unmodified

基因信息

mouse ... Cd19(12478)

一般描述

B-lymphocyte antigen CD19 (CD19), also known as Differentiation antigen CD19, is a transmembrane glycoprotein with two extracellular C2-type domains and is a critical signal transduction molecule that regulates B lymphocyte development, activation, and differentiation. CD19 expression is restricted to B cells, being absent from T cells, monocytes, and granulocytes. The CD19 antigen appears early during B cell maturation, probably at late pro-B cell stage around the time of Ig heavy chain rearrangement. It then persists during all stages of B cell maturation and is lost upon terminal differentiation to plasma cells.

免疫原

Mouse CD19-expressing K562 human erythroleukemia cells.

应用

Anti-CD19 antibody (mouse), PE, clone 6D5 is a highly specific rat monoclonal antibody & that targets CD19 & has been tested in Flow Cytometry.
Research Category
Inflammation & Immunology
Research Sub Category
Cytokines & Cytokine Receptors

质量

The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Flow Cytometry Analysis: 0.25 μg of this antibody detected in one million C57BL/6 mouse splenocytes.

目标描述

60 kDa calculated

外形

Affinity
Purified rat conjugate antibody in buffer containing PBS (pH 7.2) with up to 0.1% sodium azide.

储存及稳定性

The antibody solution should be stored undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK

WGK 2


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Lichen Zhang et al.
Immunology and cell biology, 100(9), 691-704 (2022-07-19)
Clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9 (CRISPR/Cas9) is an efficient tool for establishing genetic models including cellular models, and has facilitated unprecedented advancements in biomedical research. In both patients and cancer animal models, immune cells infiltrate the tumor

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