产品名称
抗-SNAI1抗体,克隆10H4.1, clone 10H4.1, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
10H4.1, monoclonal
species reactivity
human, rat, mouse
technique(s)
immunohistochemistry: suitable
western blot: suitable
isotype
IgMκ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SNAI1(6615)
Analysis Note
通过蛋白质印迹法在大鼠肾组织裂解物中进行评价。
蛋白质印迹分析:0.5 µg/mL的该抗体在10 µg大鼠肾脏组织裂解物中检测到SNAIL1。
蛋白质印迹分析:0.5 µg/mL的该抗体在10 µg大鼠肾脏组织裂解物中检测到SNAIL1。
Application
抗Snai1抗体(克隆10H4.1)是一种高度特异性的小鼠单克隆抗体,其靶向锌指蛋白,&已在蛋白质印迹 & IHC中进行了检验。
研究子类别
转录因子
转录因子
研究类别
表观遗传学&核功能
表观遗传学&核功能
蛋白质印迹分析:0.5 µg/mL的代表性批次在10 µg人和小鼠肾组织裂解物中检测到SNAIL1。
免疫组织化学分析:一个代表性批次以1:50稀释度在人肾切片和人扁桃体切片组织中检测到SNAIL1。
免疫组织化学分析:一个代表性批次以1:50稀释度在人肾切片和人扁桃体切片组织中检测到SNAIL1。
Disclaimer
除非我们的目录或产品随附的其他公司文件中另有说明,否则我们的产品预期仅用于研究用途,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或对人类或动物的任何类型的消费或应用。
General description
SNAI1,也称为Snail同系物1,是一种转录因子,可下调中胚层内外胚层基因的表达,并被认为对发育中的胚胎中胚层形成至关重要。SNAI1在肾脏以及间充质和上皮细胞系中表达。SNAI1中的突变与肿瘤有关。
观测分子量〜29 kDa
Immunogen
对应于人SNAIL1 N末端的KLH偶联线性肽。
表位:N末端
Other Notes
浓度:关于批次特定浓度请参见检验报告。
Physical form
形式:纯化
纯化的小鼠单克隆IgMκ,溶于含0.05%叠氮化钠的PBS的缓冲液中。
Preparation Note
自接收之日起,在2-8°C下可稳定保存1年。
未找到合适的产品?
试试我们的产品选型工具.
存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Li-Ting Wang et al.
EMBO reports, 21(2), e48795-e48795 (2020-01-08)
Epigenetic regulation is important for cancer progression; however, the underlying mechanisms, particularly those involving protein acetylation, remain to be fully understood. Here, we show that p300/CBP-associated factor (PCAF)-dependent acetylation of the transcription factor intestine-specific homeobox (ISX) regulates epithelial-mesenchymal transition (EMT)
Jia-Xing Sun et al.
Angiogenesis, 21(3), 635-652 (2018-04-21)
Ocular neovascularization is a comprehensive process involved in retinal vascular development and several blinding diseases such as age-related macular degeneration and retinopathy of prematurity, with vascular endothelial growth factor (VEGF) regarded as the master regulator. However, the qualified effect of
Menggui Huang et al.
Nature cardiovascular research, 1(4), 372-388 (2022-05-17)
Myocardial infarction (MI) is a leading cause of death worldwide, largely because efficient interventions to restore cardiac function after MI are currently lacking. Here, we characterize vascular aberrancies induced by MI, and propose to target acquired endothelial cell (EC) changes
Jeong Ae Park et al.
PLoS genetics, 11(7), e1005324-e1005324 (2015-07-07)
Vascular branching morphogenesis is activated and maintained by several signaling pathways. Among them, vascular endothelial growth factor receptor 2 (VEGFR2) signaling is largely presented in arteries, and VEGFR3 signaling is in veins and capillaries. Recent reports have documented that Snail
Hemin-Induced Endothelial Dysfunction and Endothelial to Mesenchymal Transition in the Pathogenesis of Pulmonary Hypertension Due to Chronic Hemolysis.
Gonzales, et al.
International Journal of Molecular Sciences, 23 (2023)
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持