Anti-CD73, clone AA60-E3-3, Alexa Fluor^™ 488 conjugate Antibody

CD73, also known as Ecto-5′-nucleotidase, catalyzes the conversion of purine 5′ mononucleotides to nucleosides, the preferred substrate being AMP. The enzyme consists of a dimer of 2 identical 70-kD subunits bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane. The enzyme is used as a marker of lymphocyte differentiation, being expressed on subsets of B-cells and T-cells. CD73 is also a marker of undifferentiated mesenchymal stem cells and is often used to identified stem cell populations.

Whole Mouse Dermal Lymphatic Endothelial Cells (DLEC)

Evaluated by Immunocytochemistry on human bone marrow mesenchymal stem cells. Immunocytochemical analysis: A 1:50 dilutions of this antibody detected CD73 on 1X10^6 human adipose and bone marrow mesenchymal stem cells.

Research Category
Stem Cell Research

Research Sub Category
Mesenchymal Stem Cells

This Anti-CD73, clone AA60-E3-3 is validated for use in Immunocytochemistry for the detection of CD73.

Evaluated by Immunocytochemistry on human adipose mesenchymal stem cells.
Immunocytochemical analysis: A 1:50 dilutions of this antibody detected CD73 on 1X10^6 human adipose and bone marrow mesenchymal stem cells.

The unconjugated parent antibody (Catalog No. MABD122) has an observed MW at 63 kDa

Protein G Purified

Purified mouse monoclonal IgG1κ conjugated to Alexa Fluor^™ 488 in PBS with 0.1% sodium azide and 15mg/ml BSA.

Maintain refrigerated at 2-8ºC protected from light in undiluted aliquots for up to 6 months from date of receipt.

Concentration: Please refer to lot specific datasheet.

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