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Merck
CN
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主要文件

MABC699

Sigma-Aldrich

Anti-PAX3, clone 7D8G7 Antibody

ascites fluid, clone 7D8G7, from mouse

别名:

Paired box protein Pax-3, HuP2

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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

mouse

质量水平

抗体形式

ascites fluid

抗体产品类型

primary antibodies

克隆

7D8G7, monoclonal

种属反应性

human, rat, mouse

技术

ELISA: suitable
western blot: suitable

同位素/亚型

IgG1

UniProt登记号

运输

wet ice

靶向翻译后修饰

unmodified

基因信息

human ... PAX3(5077)

一般描述

Paired box protein Pax-3, also known as HuP2, and encoded by the gene name PAX3 or HUP2, is a transcription factor that may be involved in regulating cell proliferation, migration, and apoptosis. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma.

免疫原

Purified recombinant fragment of human PAX3 expressed in E. Coli

应用

Detect PAX3 using this Anti-PAX3, clone 7D8G7 Antibody validated for use in western blotting & ELISA.
ELISA: A representative lot was used on control antigen (100 ng) and Antigen (10 ng, 50 ng, 100 ng) in ELISA (Direct).
Research Category
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional

质量

Evaluated by Western Blotting in A549, A431, Jurkat, rat spleen, and mouse liver lysates.

Western Blotting Analysis: A 1:500-1:2,000 dilution of this antibody detected PAX3 in A549, A431, Jurkat, rat spleen, and mouse liver lysates.

目标描述

~53 kDa observed. Uncharacterized bands may be observed in some lysate(s).

外形

Unpurified
Mouse monoclonal IgG1 ascitic fluid with up to 0.1% sodium azide.

储存及稳定性

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

12 - Non Combustible Liquids

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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