Anti-LAMP-1 (CD107a) Antibody, clone 1D4B

Lysosome-associated membrane protein 1 (LAMP-1) is a highly glycosolated, single-pass type 1 membrane protein belonging to the lysosome- associated membrane protein family; a group of proteins that make up the majority of the lysosomal membrane and are considered crucial mediators for cellular adhesion by interacting with carbohydrate receptors. LAMP-1 functions to traffic carbohydrate ligands to selectins. It is also thought to play a role in tumor cell metastasis.

NIH/3T3 plasma membrane fraction of mouse LAMP-1.

Detect LAMP-1 (CD107a) using this Anti-LAMP-1 (CD107a) Antibody, clone 1D4B validated for use in WB, IP, IC, IH, FC.

Immunoprecipitation Analysis: A previous lot was used by an independent laboratory in IP (Chen, 1985).

Immunocytochemistry Analysis: A previous lot was used by an independent laboratory in IC (Chen, 1985).

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

Tumor Markers

Evaluated by Western Blot in NIH/3T3 cell lysate.

Western Blot Analysis: 1:50,000 dilution of this antibody detected LAMP-1 in 10 µg of NIH/3T3 cell lysate.

~ 100 kDa observed. The calculated molecular weight of this protein is 44 kDa The protein is heavily glycosolated and therefore its molecular weight is typically noted from 95-115 kDa

Protein G

Format: Purified

Purified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Control
NIH/3T3 cell lysate

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