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生物来源
mouse
质量水平
抗体形式
purified immunoglobulin
克隆
1A4B.6, monoclonal
种属反应性
human
制造商/商品名称
Chemicon®
技术
ELISA: suitable
immunofluorescence: suitable
inhibition assay: suitable (hemagglutination)
同位素/亚型
IgG2b
运输
wet ice
特异性
The MAb 1A4B-6 is an IgG2b antibody that reacts with an
E1 epitope shared by all alphaviruses. Encephalitis Virus: Strains Indentified:
Eastern Equine (EEE) N. American eastern equine (NJ/60);
S. American eastern equine (BeAn 5122)
Western Equine (WEE) Western equine (McMIllan); Highlands J (B-230);
Sindbis
Semliki Forest Semliki Forest
Venezuelan Equine (VEE) 1AB (TC-83 Vaccine, Trinidad Donkey, PTF-39);
1C (P676); 1D (3880); 1E ( Mena II);
1F(78V-3531); 2 (Fe3-7c); 3 (Mucambo);
4 (Pixuna); 5 (Cabassou)
E1 epitope shared by all alphaviruses. Encephalitis Virus: Strains Indentified:
Eastern Equine (EEE) N. American eastern equine (NJ/60);
S. American eastern equine (BeAn 5122)
Western Equine (WEE) Western equine (McMIllan); Highlands J (B-230);
Sindbis
Semliki Forest Semliki Forest
Venezuelan Equine (VEE) 1AB (TC-83 Vaccine, Trinidad Donkey, PTF-39);
1C (P676); 1D (3880); 1E ( Mena II);
1F(78V-3531); 2 (Fe3-7c); 3 (Mucambo);
4 (Pixuna); 5 (Cabassou)
免疫原
Epitope: Virus
应用
Detect the Eastern Equine Encephalitis protein using this Anti-Eastern Equine Encephalitis, Virus, clone 1A4B.6 validated for use in ELISA, IF & Hemagglutination Inhibition.
ELISA
Indirect Immunofluorescence
Hemagglutination Inhibition
Optimal working dilutions must be determined by end user.
Indirect Immunofluorescence
Hemagglutination Inhibition
Optimal working dilutions must be determined by end user.
外形
Format: Purified
Purified immunoglobulin. Liquid in PBS with 0.1% Sodium Azide.
储存及稳定性
Maintain at 2 to 8°C for up to 12 months from date of receipt.
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Detection of eastern equine encephalitis virus in infected mosquitoes using a monoclonal antibody-based antigen-capture enzyme-linked immunosorbent assay
Brown, T M, et al
The American Journal of Tropical Medicine and Hygiene, 65, 208-213 (2001)
Matthew S Sutton et al.
Cell, 186(12), 2672-2689 (2023-06-10)
Alphaviruses are RNA viruses that represent emerging public health threats. To identify protective antibodies, we immunized macaques with a mixture of western, eastern, and Venezuelan equine encephalitis virus-like particles (VLPs), a regimen that protects against aerosol challenge with all three
A J Johnson et al.
Journal of clinical microbiology, 38(5), 1827-1831 (2000-05-02)
Monoclonal antibody (MAb)-based capture enzyme-linked immunosorbent assays (ELISAs) for the detection of anti-arboviral immunoglobulin G (IgG ELISAs) were developed for a comprehensive array of medically important arboviruses from the Alphavirus, Flavivirus, and Bunyavirus genera. Tests were optimized and standardized so
JinZhu Ma et al.
Biotechnology journal, 16(8), e2100008-e2100008 (2021-06-28)
Western equine encephalitis virus (WEEV) causes lethal encephalitis in humans and equines, and it poses a serious public health threat in many countries. Therefore, the development of an efficient vaccine remains an important challenge for the prevention of WEEV infection.
Efficient functional pseudotyping of oncoretroviral and lentiviral vectors by Venezuelan equine encephalitis virus envelope proteins
Kolokoltsov, Andrey A, et al
Journal of virology, 79, 756-763 (2005)
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