推荐产品
生物来源
mouse
质量水平
抗体形式
ascites fluid
克隆
7/48-7a, monoclonal
种属反应性
human
制造商/商品名称
Chemicon®
技术
immunofluorescence: suitable
同位素/亚型
IgG1
运输
wet ice
一般描述
Adenoviruses are 65-80 nm, non-enveloped, regular icosahedron pathogens often associated with respiratory and gastrointestinal illness as well as conjunctivitis. Well over 40 types of adenoviruses have currently been recognized. In addition to their deleterious effects, adenoviruses have been used in vaccine production and in gene therapy. They also have the ability to trigger cell proliferation by interfering with host cellular anti-oncogenes. Since they are easy to prepare, multiple quickly and efficiently, and have the ability to infect and deliver their genome (including researcher-created constructs) to the nucleus of a variety of post-mitotic cells, adenoviruses are extremely valuable in research and medical applications ranging from virus/host cell interaction to the insertion of novel genes or regulatory mechanisms into eukaryotic cellular systems, to delivery of therapeutic anti-cancer genes.
特异性
Adenovirus 1,2,5,6
免疫原
Adenovirus 1,2,5,6 hexon protein
应用
Anti-Adenovirus 1, 2, 5, 6 Antibody, clone 7/48-7a is an antibody against Adenovirus 1 for use in IF.
IFA.
Optimal working dilutions must be determined by end user.
Optimal working dilutions must be determined by end user.
Research Category
Infectious Diseases
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral
Infectious Diseases - Viral
外形
Ascites
储存及稳定性
Maintain at -20°C in convenient aliquots for up to 12 months. Do not store in a diluted format.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Infection with replication-deficient adenovirus induces changes in the dynamic instability of host cell microtubules.
Warren, JC; Rutkowski, A; Cassimeris, L
Molecular Biology of the Cell null
Rapid detection and serotyping of adenovirus by direct immunofluorescence.
Wood, S R, et al.
Journal of Medical Virology, 51, 198-201 (1997)
Weidong Xu et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 22(8), 1504-1517 (2014-05-06)
We are interested in developing oncolytic adenoviruses for the treatment of prostate cancer (PCa) bone metastases. A key limitation of Adenovirus 5 (Ad5) is that upon systemic administration, it produces major liver and systemic toxicities. To address this issue, a
The contributions of microtubule stability and dynamic instability to adenovirus nuclear localization efficiency.
James C Warren,Lynne Cassimeris
Cell Motility and the Cytoskeleton null
Natalya Kaverina et al.
Autophagy, 13(11), 1905-1923 (2017-10-06)
Formation of metastases, also known as cancer dissemination, is an important stage of breast cancer (BrCa) development. KISS1 expression is associated with inhibition of metastases development. Recently we have demonstrated that BrCa metastases to the brain exhibit low levels of
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