产品名称
抗-髓磷脂少突胶质细胞糖蛋白（MOG）抗体, clone 8-18C5, Chemicon®, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
8-18C5, monoclonal
species reactivity
rat, mouse
manufacturer/tradename
Chemicon®
technique(s)
flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
isotype
IgG1
GenBank accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
mouse ... Mog(17441)
Analysis Note
对照
脑裂解物
脑裂解物
通过免疫印迹进行了常规评估。
Application
抗髓鞘少突胶质细胞糖蛋白(MOG)抗体是一种抗髓鞘少突胶质细胞糖蛋白(MOG)的抗体，用于FC、IC、IH&WB。
研究子类别
神经元&神经胶质标志物
神经元&神经胶质标志物
研究类别
神经科学
神经科学
Biochem/physiol Actions
MOG[髓鞘少突胶质细胞糖蛋白]的膜相关区域。
基于序列相似性，可能与人和牛发生交叉反应。
Disclaimer
除非我们的目录或产品随附的其他公司文件中另有说明，否则我们的产品预期仅用于研究用途，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或对人类或动物的任何类型的消费或应用。
General description
28 kDa
髓鞘少突胶质细胞糖蛋白(MOG)是多发性硬化症原发性脱髓鞘的关键CNS特异性自身抗原。尽管已经确定了MOG的疾病诱导作用，但其在中枢神经系统中的确切功能仍然不清楚。 MOG是具有单个细胞外Ig可变域（Ig-V）（3、13、14）的I型整合膜蛋白。MOG的氨基酸序列在动物物种中高度保守（>90%），表明其重要的生物学功能。MOG在髓鞘最外层的中枢神经系统以及少突胶质细胞的细胞体和过程中特异性表达。MOG的发育后期表达与髓鞘生成的后期相关，表明MOG在髓鞘的完成、紧实和/或维持中起作用，进一步表明MOG在CNS中具有粘附功能。与MOG′在CNS中可能的粘附作用一致，MOG的同型二聚体形式不仅在与CNS分离后观察到，而且还在原位观察到。
Immunogen
大鼠小脑糖蛋白
表位：该抗体与MOG的细胞外免疫球蛋白V样结构域上存在的不连续表位结合。
Other Notes
浓度：关于批次特定浓度请参见检验报告。
Physical form
形式：纯化
纯化免疫球蛋白
纯化品，溶于0.1 M Tris-甘氨酸, 0.15 M NaCl, pH 7.4和0.05%叠氮化钠
Preparation Note
自收到之日起，以未稀释的等分试样在2-8°C下可保存长达1年。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
GenBank is a registered trademark of United States Department of Health and Human Services
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存储类别
10 - Combustible liquids
wgk
WGK 2
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