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生物来源
rat
质量水平
抗体形式
culture supernatant
抗体产品类型
primary antibodies
克隆
monoclonal
种属反应性
mouse, rat
制造商/商品名称
Chemicon®
技术
immunohistochemistry: suitable
western blot: suitable
同位素/亚型
IgG1
NCBI登记号
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
mouse ... Hcn2(15166)
rat ... Hcn2(114244)
特异性
HCN2 (Hyperpolarization-activated and cyclic nucleotide-gated channel 2). The antibody recognizes both the glycosyated and deglycosylated form of HCN2. The antibody recognizes a weak band at ~98 kDa and a stronger band at ~108 kDa in glycosylated protein from a retinal membrane preparation.
免疫原
Synthetic peptide from rat HCN2.
应用
Anti-HCN2 Antibody is an antibody against HCN2 for use in IH & WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Ion Channels & Transporters
Ion Channels & Transporters
Western blot on rat and mouse retina. The antibody recognizes a weak band at ~98 kDa and a stronger band at ~108 kDa in glycosylated protein from a retinal membrane preparation.
Immunohistochemistry on rat and mouse retina.
Optimal working dilutions must be determined by end user.
Immunohistochemistry on rat and mouse retina.
Optimal working dilutions must be determined by end user.
外形
Cultured supernatant containing 0.05% sodium azide.
储存及稳定性
Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Joon Ha Park et al.
International journal of molecular medicine, 44(5), 1801-1810 (2019-10-02)
Hyperpolarization‑activated cyclic nucleotide‑gated (HCN) channels have been known to participate in the regulation of neuronal excitability, synaptic transmission and long‑term potentiation in the hippocampus. The present study investigated transient ischemia‑induced changes of HCN1 and HCN2 expressions in the Cornu Ammonis
Stuart M Cain et al.
Pflugers Archiv : European journal of physiology, 467(6), 1367-1382 (2014-06-24)
Burst-firing in distinct subsets of thalamic relay (TR) neurons is thought to be a key requirement for the propagation of absence seizures. However, in the well-regarded Genetic Absence Epilepsy Rats from Strasbourg (GAERS) model as yet there has been no
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