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生物来源
mouse
质量水平
抗体形式
ascites fluid
克隆
1G9.39A5, monoclonal
种属反应性
human, mouse, rat, rabbit
制造商/商品名称
Chemicon®
技术
western blot: suitable
同位素/亚型
IgG2b
NCBI登记号
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
human ... GRIN2D(2906)
特异性
NMDAR2D，C末端。通过蛋白质印迹法，抗体与约145的弱条带反应。根据所用样品和抗体浓度，可观察到约75 kDa的额外条带。
免疫原
来自大鼠NMDAR2D的重组蛋白。
应用
抗NMDAR2D抗体检测NMDAR2D水平，&已发布&验证可用于WB。
研究子类别
神经递质&受体
神经递质&受体
研究类别
神经科学
神经科学
蛋白质印迹：针对大鼠脑裂解物为1:500-1:1,000。
最佳工作稀释度必须由最终使用者进行确定。
最佳工作稀释度必须由最终使用者进行确定。
外形
液体。
储存及稳定性
接收后，以未稀释的等分试样在-20°C下保存长达6个月。应避免反复冻/融循环。
分析说明
对照
大鼠前脑或小脑。
大鼠前脑或小脑。
其他说明
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
除非我们的目录或产品随附的其他公司文件中另有说明，否则我们的产品预期仅用于研究用途，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或对人类或动物的任何类型的消费或应用。
储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Sharon A Swanger et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(48), 15971-15983 (2015-12-04)
The GluN2D subunit of the NMDA receptor is prominently expressed in the basal ganglia and associated brainstem nuclei, including the subthalamic nucleus (STN), globus pallidus, striatum, and substantia nigra. However, little is known about how GluN2D-containing NMDA receptors contribute to
Gajanan P Shelkar et al.
Scientific reports, 9(1), 7572-7572 (2019-05-22)
The GluN2C- and GluN2D-containing NMDA receptors are distinct from GluN2A- and GluN2B-containing receptors in many aspects including lower sensitivity to Mg2+ block and lack of desensitization. Recent studies have highlighted the unique contribution of GluN2C and GluN2D subunits in various
Marie A Doyle et al.
Neuropharmacology, 225, 109377-109377 (2022-12-18)
Stress coping strategies represent critical responses to environmental challenges, and active coping has been linked to stress resilience in humans. Understanding the neuroadaptations that support these strategies may provide insights into adaptive and maladaptive stress responses. NMDA receptors (NMDARs) play
H Wang et al.
Neuroscience, 188, 168-181 (2011-05-21)
Untimely activation of nicotinic acetylcholine receptors (nAChRs) by nicotine results in short- and long-term consequences on learning and behavior. In this study, the aim was to determine how prenatal nicotine exposure affects components of glutamatergic signaling in the hippocampus during
Riley E Perszyk et al.
Molecular pharmacology, 90(6), 689-702 (2016-11-03)
N-methyl-d-aspartate receptors (NMDARs) are ionotropic glutamatergic receptors that have been implicated in learning, development, and neuropathological conditions. They are typically composed of GluN1 and GluN2A-D subunits. Whereas a great deal is known about the role of GluN2A- and GluN2B-containing NMDARs
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