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Merck
CN
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主要文件

MAB5550

Sigma-Aldrich

Anti-TorsinA Antibody

ascites fluid, Chemicon®

别名:

Anti-AMC5, Anti-DYT1

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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

mouse

质量水平

抗体形式

ascites fluid

抗体产品类型

primary antibodies

克隆

monoclonal

种属反应性

mouse, rat, human

制造商/商品名称

Chemicon®

技术

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

同位素/亚型

IgG1

NCBI登记号

UniProt登记号

运输

dry ice

靶向翻译后修饰

unmodified

基因信息

human ... TOR1B(27348)

一般描述

TorsinA can regulate the cellular trafficking of the dopamine transporter, as well as other polytopic membrane-bound proteins, including G protein-coupled receptors, transporters, and ion channels. TorsinA is found in the dopamine neurons that are lost in PD, and is a component of Lewy bodies. in addition, a genetic defect in TorsinA underlies Torsion dystonia, a disease characterized by painful muscle contractions that result in uncontrollable distortions.

特异性

TorsinA

免疫原

Maltose binding protein fusion protein from human torsinA.

应用

Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience

Neurodegenerative Diseases
This Anti-TorsinA Antibody is validated for use in IP, WB, IC for the detection of TorsinA.

目标描述

37kDa

外形

Ascites
Liquid. Contaings no preservative

储存及稳定性

Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.

分析说明

Control
Positive Control: Human brain lysate, NGF treated PC12 cells.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Diminishing evidence for torsinA-positive neuronal inclusions in DYT1 dystonia.
Drew Pratt et al.
Acta neuropathologica communications, 4(1), 85-85 (2016-08-18)

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