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Merck
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主要文件

MAB5280X

Sigma-Aldrich

Anti-Tyrosine Hydroxylase Antibody, clone 2/40/15, Alexa Fluor 488

clone 2/40/15, Chemicon®, from mouse

别名:

Anti-DYT14, Anti-DYT14|, Anti-DYT5b, Anti-TYH

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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

mouse

质量水平

偶联物

ALEXA FLUOR 488

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

2/40/15, monoclonal

种属反应性

rat, bovine, quail, chicken

制造商/商品名称

Chemicon®

技术

immunohistochemistry: suitable

同位素/亚型

IgG2a

UniProt登记号

运输

wet ice

靶向翻译后修饰

unmodified

基因信息

rat ... Th(25085)

特异性

Tyrosine hydroxylase (TH) catalyzes the rate-determining initial step in the biosynthesis of catecholamines such as dopamine, noradrenaline and adrenaline. Therefore the antibody is used to stain dopaminergeous and adrenergeous neurons as well as the chromaffine tissue of the adrenal medulla. Cell lines such as the PC 12 line, which is derived from a rat pheochromocytoma also, show positive reactions. In immunoblots of adrenal medulla tissue, the antibody recognizes a single protein band in the molecular weight range of 56 - 60 kD.

免疫原

Purified tyrosine hydroxylase (EC 1.14.16.2) from a rat pheochromocytoma (2).

应用

Anti-Tyrosine Hydroxylase Antibody, clone 2/40/15, Alexa Fluor 488 is an antibody against Tyrosine Hydroxylase for use in IH.
Immunohistochemistry

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors

Neuronal & Glial Markers

外形

Purified immunoglobulin conjugated to Alexa Fluor 488. Liquid in Phosphate buffer with 15 mg/mL BSA as a stabilizer and 0.1% sodium azide.

储存及稳定性

Maintain at 2-8°C in undiluted aliquots in the dark for up to 6 months after date of receipt.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

ALEXA FLUOR is a trademark of Life Technologies
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Alexa Fluor is a registered trademark of Molecular Probes, Inc.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Thomas Haggerty et al.
The European journal of neuroscience, 33(9), 1598-1610 (2011-04-02)
Although clinically distinct diseases, tauopathies and synucleinopathies share a common genesis and mechanisms, leading to overlapping degenerative changes within neurons. In human postmortem striatum of Parkinson's disease (PD) and PD with dementia, we have recently described elevated levels of tauopathy

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