推荐产品
生物来源
mouse
质量水平
抗体形式
affinity purified immunoglobulin
克隆
monoclonal
种属反应性
human
制造商/商品名称
Chemicon®
技术
immunocytochemistry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable
同位素/亚型
IgG1
NCBI登记号
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
human ... GRIN2A(2903)
免疫原
由人NMDAR2A 的氨基酸区域1099-1213产生的GST融合蛋白。
应用
在4%多聚甲醛&0.125%戊二醛固定的组织上进行免疫组化(轻和EM):2.5-5 μg/mL。
免疫细胞化学:2.5-5.0μg/mL
蛋白质印迹:1-5 μg/mL 最佳工作稀释度必须由最终用户进行确定。
免疫细胞化学:2.5-5.0μg/mL
蛋白质印迹:1-5 μg/mL 最佳工作稀释度必须由最终用户进行确定。
抗i-NMDAR2A抗体可检测i-NMDAR2A的水平& 已有相关文献发表 &经验证可用于IH(P)、IC、IH & WB。
研究子类别
神经递质 & 受体
神经递质 & 受体
研究类别
神经科学
神经科学
联系
替代:MAB5218
外形
亲和纯化的免疫球蛋白。 溶于PBS中的液体。不含防腐剂。
形式:纯化
储存及稳定性
以未稀释的等分试样在-20°C下冷冻保存长达12 个月。应避免反复冻/融循环。
其他说明
浓度:请参考批次特异性浓缩物的检验报告。
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
储存分类代码
12 - Non Combustible Liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Regulation of NMDA receptors by cyclin-dependent kinase-5.
Proceedings of the National Academy of Sciences of the USA null
Frontiers in synaptic neuroscience, 7, 1-1 (2015-03-10)
N-methyl-D-aspartate receptors (NMDARs) in cerebellar molecular layer interneurons (MLIs) are expressed and activated in unusual ways: at parallel fibre (PF) synapses they are only recruited by repetitive stimuli, suggesting an extrasynaptic location, whereas their activation by climbing fibre is purely
Neuron, 44(2), 335-349 (2004-10-12)
Under standard conditions, cultured ventral spinal neurons cluster AMPA- but not NMDA-type glutamate receptors at excitatory synapses on their dendritic shafts in spite of abundant expression of the ubiquitous NMDA receptor subunit NR1. We demonstrate here that the NMDA receptor
Neuron, 48(5), 825-838 (2005-12-13)
While deregulation of cyclin-dependent kinase 5 (Cdk5) has been implicated in neurodegenerative diseases, its precise role in synaptic plasticity and memory remains elusive. Proteolytic cleavage of p35, a regulatory subunit of Cdk5, by calpain results in the generation of the
Neuropharmacology, 149, 195-203 (2019-01-15)
Programming of the brain by early life stress has been associated with alterations in structure and function of the dorsal hippocampus. Yet, the underlying molecular mechanisms remain largely elusive. In this study, we examined the effects of early life stress
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