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Merck
CN

MAB5208

Anti-Beta (β)-Amyloid antibody

CHEMICON®, mouse monoclonal, AB10

别名:

Anti-AAA, Anti-ABPP, Anti-AD1, Anti-APPI, Anti-CTFgamma, Anti-CVAP, Anti-PN-II, Anti-PN2, Anti-alpha-sAPP, Anti-preA4

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关于此项目

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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产品名称

Anti-Amyloid Antibody, β 1-16, clone AB10, clone AB10, Chemicon®, from mouse

biological source

mouse

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

AB10, monoclonal

species reactivity

human, monkey, bovine

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG1

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... APP(351)

Application

Anti-Amyloid Antibody, β 1-16, clone AB10 detects level of Amyloid & has been published & validated for use in ELISA, IP, WB, IC, IH.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Western blot: 1-5 µg/mL
Immunohistochemistry: 5-10 µg/mL
Immunocytochemistry: 5-10 µg/mL
ELISA: 0.2-1.0 µg/mL
Immunoprecipitation

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Amyloid-beta 1-16.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

Amyloid-beta 1-16 conjugated to KLH

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified
Purified immunoglobulin. Liquid in TRIS-buffered saline containing 1 mg/mL bovine serum albumin and 0.01% sodium azide.

Preparation Note

Maintain frozen at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Huey-Jen Tsay et al.
International journal of molecular sciences, 22(19) (2021-10-14)
Alzheimer's disease (AD) is characterized by the deposition of β-amyloid peptide (Aβ). There are currently no drugs that can successfully treat this disease. This study first explored the anti-inflammatory activity of seven components isolated from Antrodia cinnamonmea in BV2 cells
Amanda B Chai et al.
International journal of molecular sciences, 22(1) (2021-01-02)
Defective clearance mechanisms lead to the accumulation of amyloid-beta (Aβ) peptides in the Alzheimer's brain. Though predominantly generated in neurons, little is known about how these hydrophobic, aggregation-prone, and tightly membrane-associated peptides exit into the extracellular space where they deposit
Yung-Cheng Huang et al.
PloS one, 17(1), e0260966-e0260966 (2022-01-25)
Diabetes is a risk factor for Alzheimer's disease (AD), a chronic neurodegenerative disease. We and others have shown prediabetes, including hyperglycemia and obesity induced by high fat and high sucrose diets, is associated with exacerbated amyloid beta (Aβ) accumulation and
Tsai-Teng Tzeng et al.
International journal of molecular sciences, 19(2) (2018-02-22)
Hericium erinaceus was used in traditional Chinese medicine for physiologically beneficial medicines. Recently, it has become a candidate in causing positive brain health-related activities. We previously reported that Hericium erinaceus mycelium ameliorates Alzheimer's disease (AD)-related pathologies. To reveal the role

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