Anti-DPPA-2 Antibody, clone 6C1.2, Alexa Fluor^™ 488 conjugate

DPPA-2 (developmental pluripotency associated-2) is a novel Oct-4-related protein that is localized to the nucleus of mouse fetal germ cells. DPPA-2 has binding sites for both POU and Sox-2 protein domains and is expressed primarily in the developing germ line following gastrulation. These associations suggest that this protein participates in a very strong supportive role in maintaining cell pluripotentiality. In addition to its role as a pluripotency marker, more recent research using cancer cells suggests that DPPA-2 may also act as an embryo-cancer antigen—pointing to the presence of abnormal cell growth and the formation of cancerous cells.

recombinant protein corresponding to mouse DPPA-2.

Research Category
Stem Cell Research

Research Sub Category
Pluripotent & Early Differentiation

This Anti-DPPA-2 Antibody, clone 6C1.2, Alexa Fluor 488 conjugate is validated for use in ICC for the detection of DPPA-2.

Evaluated by Immunocytochemistry in Mouse Embryonic Stem Cells (SCR012). Immunocytochemsitry Analysis: A 1:100 dilution of this antibody detected SOX-2 in Mouse Embryonic Stem Cells (SCR012).

~30 kDa observed

Protein G Purified

Purified mouse monoclonal IgG2aλ supernatant in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Maintain refrigerated at 2-8ºC protected from light in undiluted aliquots for up to 6 months from date of receipt.

Control
Mouse Embryonic Stem Cells (SCR012).

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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