推荐产品
生物来源
mouse
质量水平
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
5G10.2, monoclonal
种属反应性
mouse, human
制造商/商品名称
Chemicon®
技术
ELISA: suitable
immunocytochemistry: suitable
western blot: suitable
输入
sample type induced pluripotent stem cell(s)
sample type: mouse embryonic stem cell(s)
sample type: human embryonic stem cell(s)
同位素/亚型
IgG1κ
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... UTF1(8433)
一般描述
UTF1是一种转录因子，最初是由于其在胚胎干(ES)细胞、胚胎性癌(EC)细胞和种系组织中的表达而被鉴定的。 在成人组织中未发现表达。 当时认为UTF1可能在胚胎发生的早期分子事件中起重要作用。 随后的研究表明，UTF1是Oct-4/Sox-2复合物的靶标，Oct-4/Sox-2复合物是干细胞多能性的关键决定因素
免疫原
重组GST融合蛋白，人UTF-1
应用
抗UTF-1抗体，克隆5G10.2检测UTF-1水平，&已发布&验证可用于ELISA、WB&IC。
外形
形式：纯化
其他说明
浓度：关于批次特定浓度请参见检验报告。
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
A L Caldeira-Brant et al.
Reproduction (Cambridge, England), 159(4), 437-451 (2020-01-29)
Human spermatogonial stem cells (SSCs) are an essential source to maintain spermatogenesis as an efficient process for daily sperm production with high self-renewal capacity along adulthood. However, the phenotype and the subpopulation that represent the real reserve SSC for the
Hanna Valli et al.
Fertility and sterility, 102(2), 566-580 (2014-06-04)
To determine the molecular characteristics of human spermatogonia and optimize methods to enrich spermatogonial stem cells (SSCs). Laboratory study using human tissues. Research institute. Healthy adult human testicular tissue. Human testicular tissue was fixed or digested with enzymes to produce
Xiao-Ling Wu et al.
Carcinogenesis, 34(7), 1660-1668 (2013-03-29)
Undifferentiated embryonic cell transcription factor-1 (UTF1) is an important transcription factor during development, which plays critical roles in cell fate determination. However, its expression and function in somatic tissues remain unclear. Here, we investigated the expression pattern of the UTF1
Sabine Conrad et al.
Stem cells international, 2016, 8582526-8582526 (2015-12-10)
The aim of this study was to elucidate the molecular status of single human adult germ stem cells (haGSCs) and haGSC colonies, which spontaneously developed from the CD49f MACS and matrix- (collagen-/laminin+ binding-) selected fraction of enriched spermatogonia. Single-cell transcriptional
H Valli-Pulaski et al.
Human reproduction (Oxford, England), 34(6), 966-977 (2019-05-22)
Is it feasible to disseminate testicular tissue cryopreservation with a standardized protocol through a coordinated network of centers and provide centralized processing/freezing for centers that do not have those capabilities? Centralized processing and freezing of testicular tissue from multiple sites
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