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Merck
CN

MAB4331

Anti-MELK Antibody, clone 6C1.3

clone 6C1.3, Chemicon®, from mouse

别名:

Maternal Embryonic Leucine Zipper Kinase

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UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

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产品名称

Anti-MELK Antibody, clone 6C1.3, clone 6C1.3, Chemicon®, from mouse

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

6C1.3, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

input

sample type neural stem cell(s)

isotype

IgG2κ

NCBI accession no.

NM_014791.2

UniProt accession no.

Q14680

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... MELK(9833)

Application

Research Category
Stem Cell Research
Research Sub Category
Neural Stem Cells
This Anti-MELK Antibody, clone 6C1.3 is validated for use in WB for the detection of MELK.
Western blot: Recommended dilution: 1:500 (2 μg/mL)
Expected Molecular Weight: 74.5 kDa
Note: Bands may be present at a higher molecular weight due to glycosolation.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

74.5 kDA; glycosylations may result in higher MW bands in western blot.
Melk, (Maternal Embryonic Leucine Zipper Kinase) is a serine-threonine kinase of the snfI/AMPK family that is expressed in developing neuroepithelium, self-renewing neural stem cells and granule cell precursors. It is also considered an important brain tumor marker, being highly expressed in gliobastoma, astrocytomas, and medulablastomas.

Immunogen

MELK Recombinant protein.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified
Purified immunoglobulin in PBS, pH 7.0. Contains 0.1% sodium azide.

Preparation Note

1 year at 2-8 °C from date of shipment

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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As the focus of stem cell research undergoes a transition from animal to human models, researchers are in critical need of validated products to support the isolation, maintenance, differentiation, and characterization of human stem cells. While many reagents designed for rodent systems can be applied to human stem cell studies, they are not truly optimized for robust human stem cell culture or analysis. This is why human stem cell researchers have always trusted EMD Millipore, the first provider of commercially available human embryonic stem cells and human neural stem cell lines, to accelerate their research. All of our human stem cell systems are extensively tested in defined media culture, and differentiated progeny are comprehensively characterized with highly validated antibodies and detection reagents.

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