生物来源
mouse
质量水平
抗体形式
ascites fluid
抗体产品类型
primary antibodies
克隆
monoclonal
种属反应性
human, mouse
制造商/商品名称
Chemicon®
技术
ELISA: suitable
immunocytochemistry: suitable
western blot: suitable
同位素/亚型
IgG2a
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
human ... PPARA(5465)
一般描述
过氧化物酶体增殖物激活受体（PPAR）是核激素受体，可以被多种化合物激活，包括原纤维、噻唑烷二酮、前列腺素和脂肪酸。已经描述了三种PPAR亚型，称为PPARα、PPARβ（也称为PPARδ）和PPARγ。PPAR通过与类固醇受体的类视黄醇X受体(RXR)家族成员形成异二聚体并与称为PPAR反应元件(PPRE)的特定DNA基序结合来促进转录。PPARα在原代肝细胞中含量很高，它调节参与脂肪酸代谢的蛋白质的表达。PPARβ是分布最广泛的亚型，通常以高水平表达。PPARγ主要存在于脂肪组织中，在调节脂肪细胞分化中起关键作用。
特异性
与过氧化物酶体增殖物激活受体α（PPARalpha）反应。与PPARbeta或PPARgamma无交叉反应。
免疫原
来自小鼠PPARalpha氨基酸18-34的合成肽。
应用
使用经ELISA、WB、ICC验证的抗PPAR α抗体（小鼠单克隆抗体）检测PPAR alpha，也称为过氧化物酶体增殖物激活受体α。
研究子类别
转录因子
转录因子
研究类别
表观遗传学&核功能
表观遗传学&核功能
蛋白质印迹：1:500-1:5000
免疫细胞化学：1:500-1:5000
ELISA：1:500-1:5,000
最佳工作稀释度必须由最终用户确定。
免疫细胞化学：1:500-1:5000
ELISA：1:500-1:5,000
最佳工作稀释度必须由最终用户确定。
外形
腹水液。 液体。不含防腐剂。
储存及稳定性
接收后，以未稀释的等分试样在-20°C下保存长达6个月。应避免反复冻/融循环。
分析说明
对照
3T3全细胞裂解物
3T3全细胞裂解物
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
除非我们的目录或产品随附的其他公司文件中另有说明，否则我们的产品预期仅用于研究用途，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或对人类或动物的任何类型的消费或应用。
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WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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