推荐产品
生物来源
mouse
质量水平
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
5.2F, monoclonal
种属反应性
rat, mouse, chicken, human
制造商/商品名称
Chemicon®
技术
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
同位素/亚型
IgG2a
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... MYOD1(4654)
特异性
识别MyoD1。该表位位于小鼠MyoD1蛋白N末端的3-56位氨基酸。
免疫原
来自小鼠MyoD1的重组蛋白。
应用
抗MyoD1抗体是一种用于检测MyoD1的高质量小鼠单克隆抗体，&已在ICC、IHC、IP & WB中进行了验证。
蛋白质印迹：1 μg/mL。与~45 kD蛋白反应。
针对冷冻和福尔马林固定、石蜡包埋组织的免疫组织化学：2-4 μg/mL。
免疫细胞化学
免疫沉淀：2 μg/mg蛋白裂解物
最佳工作稀释度必须由最终用户确定。
针对冷冻和福尔马林固定、石蜡包埋组织的免疫组织化学：2-4 μg/mL。
免疫细胞化学
免疫沉淀：2 μg/mg蛋白裂解物
最佳工作稀释度必须由最终用户确定。
目标描述
约45 kDa
外形
形式：纯化
分析说明
对照
胎儿肌肉，横纹肌肉瘤
胎儿肌肉，横纹肌肉瘤
其他说明
浓度：关于批次特定浓度请参见检验报告。
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Mark A Gillespie et al.
The Journal of cell biology, 187(7), 991-1005 (2009-12-23)
The mitogen-activated protein kinase p38-gamma is highly expressed in skeletal muscle and is associated with the dystrophin glycoprotein complex; however, its function remains unclear. After induced damage, muscle in mice lacking p38-gamma generated significantly fewer myofibers than wild-type muscle. Notably
A recurrent neomorphic mutation in MYOD1 defines a clinically aggressive subset of embryonal rhabdomyosarcoma associated with PI3K-AKT pathway mutations.
Kohsaka, S; Shukla, N; Ameur, N; Ito, T; Ng, CK; Wang, L; Lim, D; Marchetti, A; Viale et al.
Nature Genetics null
In situ mechanotransduction via vinculin regulates stem cell differentiation.
Holle, AW; Tang, X; Vijayraghavan, D; Vincent, LG; Fuhrmann, A; Choi, YS; del Alamo, JC; Engler, AJ
Stem Cells null
Francesca Megiorni et al.
Journal of hematology & oncology, 10(1), 161-161 (2017-10-08)
EPH (erythropoietin-producing hepatocellular) receptors are clinically relevant targets in several malignancies. This report describes the effects of GLPG1790, a new potent pan-EPH inhibitor, in human embryonal rhabdomyosarcoma (ERMS) cell lines. EPH-A2 and Ephrin-A1 mRNA expression was quantified by real-time PCR
L V Renna et al.
European journal of histochemistry : EJH, 58(4), 2444-2444 (2015-01-13)
Myotonic dystrophy type 1 (DM1) and type 2 (DM2) are multisystemic disorders linked to two different genetic loci and characterized by several features including myotonia, muscle weakness and atrophy, cardiac dysfunctions, cataracts and insulin-resistance. In both forms, expanded nucleotide sequences
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