跳转至内容
Merck
CN
所有图片(1)

文件

MAB3864

Sigma-Aldrich

抗-DNA/组蛋白H1抗体

Chemicon®, from mouse

登录查看公司和协议定价
所有图片(1)
别名:
Anti-H1.4, Anti-H1E, Anti-H1F4, Anti-H1s-4, Anti-HIST1H1E, Anti-RMNS, Anti-dJ221C16.5
UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

mouse

质量水平

100

抗体形式

purified antibody

抗体产品类型

primary antibodies

克隆

monoclonal

种属反应性（根据同源性预测）

all

制造商/商品名称

Chemicon®

技术

ELISA: suitable
flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable

同位素/亚型

IgG2a

NCBI登记号

NM_005321.2

UniProt登记号

P10412

运输

wet ice

靶向翻译后修饰

unmodified

基因信息

human ... H1-1(3024)

相关类别

特异性

与DNA/组蛋白1反应。该抗体可用于染色所有物种的细胞核并鉴定坏死。通过免疫组织化学，抗体显示细胞核密集染色，未观察到核仁染色。

免疫原

人Raji细胞核

应用

免疫细胞化学：5-10 μg/mL用于2%多聚甲醛固定的细胞（室温10分钟）

免疫组织化学：5-10 μg/mL用于多聚甲醛或B5固定的组织切片。

流式细胞术：5-10 μg/mL，使用2%多聚甲醛固定的细胞。

ELISA、直接和间接

最佳工作稀释度必须由最终用户确定。

染色模式：

观察到核染色。细胞核浓染。核仁无染色。
抗DNA/组蛋白H1抗体是用于检测DNA/组蛋白H1的高质量小鼠单克隆抗体，&已在ELISA、FC、ICC & IHC中进行了验证。
研究子类别
组蛋白
研究类别
表观遗传学&核功能

外形

形式：纯化
蛋白A纯化的培养物上清液。 溶于PBS中的液体

储存及稳定性

自接收之日起，以未稀释的等分试样在-20°C下保存长达6个月。应避免反复冻/融循环。

其他说明

浓度：关于批次特定浓度请参见检验报告。

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

除非我们的目录或产品随附的其他公司文件中另有说明，否则我们的产品预期仅用于研究用途，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或对人类或动物的任何类型的消费或应用。

WGK

WGK 2

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Gang Liu et al.
Mucosal immunology, 12(4), 862-873 (2019-04-13)
Extra-intestinal manifestations (EIM) are common in inflammatory bowel disease (IBD). One such EIM is sub-clinical pulmonary inflammation, which occurs in up to 50% of IBD patients. In animal models of colitis, pulmonary inflammation is driven by neutrophilic infiltrations, primarily in
Verena Peek et al.
Pharmaceuticals (Basel, Switzerland), 14(6) (2021-07-03)
High mobility group box (HMGB)1 action contributes to late phases of sepsis, but the effects of increased endogenous plasma HMGB1 levels on brain cells during inflammation are unclear. Here, we aimed to further investigate the role of HMGB1 in the
Nicole de Buhr et al.
Frontiers in microbiology, 9, 966-966 (2018-06-06)
Granulocytes mediate the first line of defense against infectious diseases in humans as well as animals and they are well known as multitasking cells. They can mediate antimicrobial activity by different strategies depending on the pathogen they encounter. Besides phagocytosis
Simona Grasso et al.
Thrombosis research, 161, 36-42 (2017-11-28)
The circulating zymogen form of Factor VII activating protease (FSAP) can be activated by histones and nucleosomes in vivo. These cell-death-associated nuclear factors are also actively extruded into the extracellular space by neutrophils through a process called neutrophil extracellular trap
Nicole de Buhr et al.
Cellular microbiology, 19(2) (2016-07-28)
Streptococcus suis is an important meningitis-causing pathogen in pigs and humans. Neutrophil extracellular traps (NETs) have been identified as host defense mechanism against different pathogens. Here, NETs were detected in the cerebrospinal fluid (CSF) of S. suis-infected piglets despite the presence
查看所有相关文献

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门