Anti-c-met Antibody, clone 4AT44

Reacts with c-met/HGFR (Hepatocyte growth factor receptor). The Met receptor tyrosine kinase is the prototypical member of a small subfamily of growth factor receptors that when activated, induces mitogenic, motogenic, and morphogenic cellular responses. The ligand for c-met is hepatocyte growth factor/scatter factor (HGF/SF) and while normal HGF/SF-Met signaling is required for embryonic development, abnormal c-met signaling has been strongly implicated in tumorigenesis, particularly in the development of invasive and metastatic phenotypes.

Purified recombinant catalytic domain of human Met

Research Category
Signaling

Research Sub Category
Growth Factors & Receptors

This Anti-c-met Antibody, clone 4AT44 is validated for use in WB for the detection of c-met.

Western Blot: 1:100-1:500.

ELISA (direct): 1:1,000

Optimal working dilutions must be determined by the end user.

Replaces: 04-1051

Format: Purified

Protein G purified immunoglobulin. Liquid in PBS containing 0.09% sodium azide.

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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