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主要文件

MAB3632

Sigma-Aldrich

抗-PPAR γ1和2抗体,磷酸特异性(Ser112)

ascites fluid, Chemicon®

别名:

PPARgamma1 and 2

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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

mouse

质量水平

抗体形式

ascites fluid

抗体产品类型

primary antibodies

克隆

monoclonal

种属反应性

mouse, human

制造商/商品名称

Chemicon®

技术

ELISA: suitable
immunocytochemistry: suitable
western blot: suitable

同位素/亚型

IgG1

UniProt登记号

运输

wet ice

靶向翻译后修饰

phosphorylation (pSer112)

基因信息

human ... PPARG(5468)

特异性

识别磷酸化过氧化物酶体增殖物激活受体(PPAR)γ1和γ2。

免疫原

来自人PPARγ2(与PPARγ1相同)氨基酸107-121的磷酸化(丝氨酸112)合成肽。 与PPARα或PPARβ无同源性。
表位:磷酸特异性(Ser112)

应用

使用经ELISA、WB、ICC验证的抗PPARγ1 & 2抗体,磷酸特异性(Ser112)(小鼠单克隆抗体)检测PPARγ1 & 2(也称为过氧化物酶体增殖物激活受体γ 1 & 2)。
研究子类别
转录因子
研究类别
表观遗传学&核功能
蛋白质印迹:内源和重组蛋白上为1:500-1:5,000。

免疫细胞化学:1:500-1:5000

ELISA:1:500-1:5000

最佳工作稀释度必须由最终用户确定。

外形

腹水。 液体。 不含防腐剂。

储存及稳定性

接收后,以未稀释的等分试样在-20°C下保存长达6个月。 应避免反复冻/融循环。

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

除非我们的目录或产品随附的其他公司文件中另有说明,否则我们的产品预期仅用于研究用途,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或对人类或动物的任何类型的消费或应用。

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储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

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Larry A Denner et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(47), 16725-35a-16725-35a (2012-11-24)
We previously reported that the peroxisome proliferator-activated receptor γ (PPARγ) agonist rosiglitazone (RSG) improved hippocampus-dependent cognition in the Alzheimer's disease (AD) mouse model, Tg2576. RSG had no effect on wild-type littermate cognitive performance. Since extracellular signal-regulated protein kinase mitogen-activated protein
Dalila El Ouarrat et al.
Cell metabolism, 31(1), 162-173 (2019-11-12)
Insulin resistance is a major factor in obesity-linked type 2 diabetes. PPARγ is a master regulator of adipogenesis, and small molecule agonists, termed thiazolidinediones, are potent therapeutic insulin sensitizers. Here, we studied the role of transcriptional co-activator with PDZ-binding motif
Bo-Mi Kim et al.
International journal of molecular medicine, 43(1), 489-500 (2018-10-27)
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