推荐产品
生物来源
mouse
质量水平
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
FP5A, monoclonal
种属反应性
human
制造商/商品名称
Chemicon®
技术
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable
同位素/亚型
IgG1κ
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... SLC5A5(6528)
特异性
钠/碘同向转运体（NIS）。该表位被认为位于人类NIS的625-643氨基酸区域。该抗体可能对麦芽糖结合蛋白有一定反应性。
免疫原
与人NIS（C端）氨基酸468-643相对应的麦芽糖结合蛋白融合蛋白。
表位：氨基酸625-643
应用
使用该抗钠/碘同向转运体检测钠/碘同向转运体，a.a.625-643，克隆经验证的FP5A，以应用于IH、IH(P) & WB。
免疫印迹。该抗体可识别分子量约为97 kDa的主带以及15 kDa、30 kDa、68 kDa和160 kDa的小带。
免疫组化。该抗体对石蜡包埋组织切片有效，这些切片使用10mM柠檬酸盐缓冲蒸汽提取抗原30分钟。
最佳工作稀释度必须由最终用户进行确定。
免疫组化。该抗体对石蜡包埋组织切片有效，这些切片使用10mM柠檬酸盐缓冲蒸汽提取抗原30分钟。
最佳工作稀释度必须由最终用户进行确定。
外形
形式：纯化
其他说明
浓度：请参考批次特异性浓缩物的检验报告。
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Christina Schug et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 25(19), 5997-6008 (2019-06-15)
The innate tumor homing potential of mesenchymal stem cells (MSCs) has been used for a targeted delivery of the theranostic sodium iodide symporter (NIS) transgene into solid tumors. We have previously shown that external beam radiotherapy (EBRT) results in the
Annie Yang et al.
Journal for immunotherapy of cancer, 11(4) (2023-04-06)
Gastric cancer (GC) that metastasizes to the peritoneum is fatal. CF33 and its genetically modified derivatives show cancer selectivity and oncolytic potency against various solid tumors. CF33-hNIS and CF33-hNIS-antiPDL1 have entered phase I trials for intratumoral and intravenous treatments of
Carolin Kitzberger et al.
Molecular therapy oncolytics, 30, 238-253 (2023-09-13)
New treatment strategies are urgently needed for glioblastoma (GBM)-a tumor resistant to standard-of-care treatment with a high risk of recurrence and extremely poor prognosis. Based on their intrinsic tumor tropism, adoptively applied mesenchymal stem cells (MSCs) can be harnessed to
Rebekka Spellerberg et al.
Molecular therapy oncolytics, 27, 272-287 (2022-12-03)
Sodium iodide symporter (NIS) gene transfer for active accumulation of iodide in tumor cells is a powerful theranostic strategy facilitating both diagnostic and therapeutic application of radioiodide. In glioblastoma (GBM), the blood-brain barrier (BBB) presents an additional delivery barrier for
Danielle L Gainor et al.
JAMA otolaryngology-- head & neck surgery, 141(8), 739-744 (2015-06-05)
Sodium iodide symporter (NIS) expression in adenoid cystic carcinoma (ACC) has not been fully elucidated in the literature, and it is unclear whether radioactive iodine may be a potential therapeutic modality. To our knowledge, the present study includes the largest
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