跳转至内容
Merck
CN
所有图片(1)

主要文件

MAB3536

Sigma-Aldrich

Anti-Lamin B2 Antibody, clone LN43

clone LN43, Chemicon®, from mouse

登录查看公司和协议定价


About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

mouse

质量水平

抗体形式

culture supernatant

抗体产品类型

primary antibodies

克隆

LN43, monoclonal

种属反应性

mouse, hamster, human, Xenopus

制造商/商品名称

Chemicon®

技术

flow cytometry: suitable
immunohistochemistry: suitable
western blot: suitable

同位素/亚型

IgG1

NCBI登记号

UniProt登记号

运输

dry ice

靶向翻译后修饰

unmodified

基因信息

human ... LMNB2(84823)

一般描述

Nuclear lamins form a network of filaments at the nucleoplasmic site of the nuclear membrane. Two main subtypes of nuclear lamins can be distinguished: A-type lamins and B-type lamins. The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e. lamin A, lamin C and lamin Adel 10, while the B-type lamins include two proteins arising from two distinct genes, i.e. lamin B1 and lamin B2.

特异性

Lamin B2. Recognizes an epitope located in the C-terminal part of lamin B2.

免疫原

Detergent insoluble fraction of potoroo cell line PtK1

应用

Research Category
Cell Structure
Research Sub Category
Cytoskeleton
This Anti-Lamin B2 Antibody, clone LN43 is validated for use in FC, WB, IH for the detection of Lamin B2.
Western blotting: 1:100-1:1,000; nuclear preparations recommended; detects 67-68kDa lamin B2 protein

Immunocytochemistry on fixed cells (methanol/acetone fixation): 1:100-1:200.Flow cytometry: 1:100-1:200.

Optimal working dilutions must be determined by the end user.

外形

Format: Purified
Purified culture supernatant. Liquid in PBS containing 0.09% sodium azide.

储存及稳定性

Maintain -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

未找到合适的产品?  

试试我们的产品选型工具.

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Lucia Devitt et al.
Cell communication and signaling : CCS, 22(1), 256-256 (2024-05-06)
Melanoma is a highly heterogeneous cancer, in which frequent changes in activation of signaling pathways lead to a high adaptability to ever changing tumor microenvironments. The elucidation of cancer specific signaling pathways is of great importance, as demonstrated by the
Elisa Guffanti et al.
Journal of cell science, 121(Pt 12), 2037-2045 (2008-05-29)
Nucleolar channel systems (NCSs) are membranous organelles appearing transiently in the epithelial cell nuclei of postovulatory human endometrium. Their characterization and use as markers for a healthy receptive endometrium have been limited because they are only identifiable by electron microscopy.
Shannon E Weigum et al.
BMC neuroscience, 4, 6-6 (2003-04-17)
Nuclear objects that have in common the property of being recognized by monoclonal antibodies specific for phosphoprotein epitopes and cytoplasmic intermediate filaments (in particular, SMI-31 and RT-97) have been reported in glial and neuronal cells, in situ and in vitro.
Hilary C Archbold et al.
Scientific reports, 8(1), 4606-4606 (2018-03-17)
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are progressive neurodegenerative disorders marked in most cases by the nuclear exclusion and cytoplasmic deposition of the RNA binding protein TDP43. We previously demonstrated that ALS-associated mutant TDP43 accumulates within the cytoplasm
Jean McBryan et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 21(23), 5371-5379 (2015-08-05)
Disease recurrence is a common problem in breast cancer and yet the mechanisms enabling tumor cells to evade therapy and colonize distant organs remain unclear. We sought to characterize global expression changes occurring with metastatic disease progression in the endocrine-resistant

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门