跳转至内容
Merck
CN
所有图片(1)

文件

MAB3318

Sigma-Aldrich

抗-TIMP-3抗体(克隆136-13H4)

clone 136-13H4, Chemicon®, from mouse

登录查看公司和协议定价

别名:
Tissue Inhibitor of Metalloproteinase-3
UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

mouse

质量水平

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

136-13H4, monoclonal

种属反应性

rabbit, human

制造商/商品名称

Chemicon®

技术

immunohistochemistry: suitable (paraffin)
western blot: suitable

同位素/亚型

IgG1κ

NCBI登记号

UniProt登记号

运输

dry ice

靶向翻译后修饰

unmodified

基因信息

human ... TIMP3(7078)

特异性

与人TIMP-3发生特异性反应。 这是人组织抑制剂金属蛋白酶3(人TIMP-3)上的SWYRGWAPPDKSIINATDP的寡肽(残基170-188)的纯化鼠单克隆抗体。
MAB3318 与TIMP-3发生交叉反应,但是不与人TIMP-1 和人TIMP-2反应。

免疫原

人组织抑制剂金属蛋白酶3上的SWYRGWAPPDKSIINATDP的寡肽(残基170-188)
表位:a.a.170-188

应用

免疫印迹:2 ug/mL

免疫组织化学(石蜡):10ug/mL

免疫组织化学(冷冻):2 ug/mL
抗-TIMP-3 抗体(a.a. 170-188,克隆136-13H4)是一种针对TIMP-3的抗体,可用于 IH(P) & WB。
研究子类别
MMPs & TIMPs
研究类别
细胞结构

目标描述

26kda

外形

形式:纯化
液体溶于0.1 M磷酸钠缓冲液,pH值7.0,含有2%无蛋白酶的牛血清白蛋白。
纯化蛋白A

储存及稳定性

自收到之日起在-20°C可稳定保存1年。避免反复冻融。为了最大程度地回收产品,在融化后和取下盖子之前,将原始小瓶进行离心。

分析说明

对照
乳腺癌组织

其他说明

浓度:请参考批次特异性浓缩物的检验报告。

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

由Daiichi Fine Chemical Co., Ltd生产

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

WGK

WGK 2


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Lluis Catasus et al.
Histopathology, 62(4), 632-641 (2013-02-06)
Expression of tissue inhibitor of metalloproteinases-3 (TIMP-3) has been found to be decreased in several types of cancer by promoter gene hypermethylation. However, little is known regarding the silencing effect of TIMP3 promoter hypermethylation on gene and protein expression in
Chun-Wen Su et al.
Cell death & disease, 10(11), 793-793 (2019-10-19)
The tissue inhibitor of metalloproteinase-3 (TIMP3) is the only member of the TIMP family that binds to the extracellular matrix and suppresses cancer cell growth, angiogenesis, migration, and invasion. However, whether the abnormal expression and promoter methylation of TIMP3 facilitates
Qinglei Li et al.
Reproduction (Cambridge, England), 128(5), 555-564 (2004-10-29)
The matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) are potential regulators of the focalized extracellular matrix degradation required for ovulation. The objectives of the present study were to determine localization and temporal regulation of TIMP-3 and TIMP-4 mRNA and
S Jane Darnton et al.
International journal of cancer, 115(3), 351-358 (2005-02-03)
Amongst involvement in diverse physiological and pathological processes, TIMP-3 may have an important role in tumour development, growth and metastasis by interaction with metalloproteases in the extracellular matrix. We studied the role and prognostic effect of TIMP-3 in esophageal adenocarcinoma
Classical macrophage activation up-regulates several matrix metalloproteinases through mitogen activated protein kinases and nuclear factor-?B.
Huang, WC; Sala-Newby, GB; Susana, A; Johnson, JL; Newby, AC
Testing null

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门