biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
67-4H11, monoclonal
species reactivity
rabbit, goat, guinea pig, rat, human, bovine, mouse
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable, immunohistochemistry: suitable (paraffin), western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... TIMP2(7077)
Immunogen
Synthetic peptide corresponding to amino acids 178-193 of human TIMP-2 (numbered from the propeptide)
YRGAAPPKQEFLDIED
YRGAAPPKQEFLDIED
Application
Anti-TIMP-2 Antibody, clone 67-4H11 detects level of TIMP-2 & has been published & validated for use in ELISA, WB, IH(P).
Immunoblotting
Immunohistochemistry on paraffin-embedded, PLP fixed tissue at 5 μg/mL (see Tomita reference) or frozen tissues at 1 μg/mL (see Ohashi reference).
ElA
Immunohistochemistry on paraffin-embedded, PLP fixed tissue at 5 μg/mL (see Tomita reference) or frozen tissues at 1 μg/mL (see Ohashi reference).
ElA
Research Category
Cell Structure
Cell Structure
Research Sub Category
MMPs & TIMPs
MMPs & TIMPs
Biochem/physiol Actions
The antibody specifically reacts with human TIMP-2.
SPECIES REACTIVITY:
Cross-reacts with mouse, rat, guinea pig, rabbit and bovine TIMP-2.
SPECIES REACTIVITY:
Cross-reacts with mouse, rat, guinea pig, rabbit and bovine TIMP-2.
Physical form
Format: Purified
Liquid in 0.1M Na-Phosphate buffer, pH 7.0 containing 2% protease free bovine serum albumin.
Preparation Note
Maintain frozen at -20°C in undiluted aliquots for up to 12 months.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: MAB3356
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Manufactured by Daiichi Fine Chemical Co., Ltd
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
TNF-alpha stimulates activation of pro-MMP2 in human skin through NF-(kappa)B mediated induction of MT1-MMP.
Han, YP; Tuan, TL; Wu, H; Hughes, M; Garner, WL
Journal of Cell Science null
John Ng et al.
Investigative ophthalmology & visual science, 49(12), 5295-5306 (2008-07-22)
Ocular surface squamous neoplasia (OSSN) is an uncommon tumor of the corneal and conjunctival epithelium associated with risk of permanent visual impairment. The purposes of this study were to (1) identify and localize potential mediators in tissue from patients with
Wenni Tong et al.
Developmental neurobiology, 70(3), 182-194 (2009-12-18)
A recent study has shown that increased activity of matrix metalloproteinases-2 and metalloproteinases-9 (MMP-2 and MMP-9) has detrimental effect on the brain after neonatal hypoxia. The present study determined the effect of maternal hypoxia on neuronal survivability and the activity
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| MAB3310 | 04053252467035 |