跳转至内容
Merck
CN

MAB3303

抗VI型胶原抗体,克隆VI-26

clone VI-26, Chemicon®, from mouse

别名:

Anti-BTHLM1, Anti-OPLL, Anti-UCHMD1

登录 查看组织和合同定价。

选择尺寸


关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
VI-26, monoclonal
Application:
ELISA
immunohistochemistry
Species reactivity:
human, rabbit
Citations:
28
Technique(s):
ELISA: suitable
immunohistochemistry: suitable (paraffin)
Uniprot accession no.:
技术服务
需要帮助?我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助?我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

产品名称

抗VI型胶原抗体,克隆VI-26, clone VI-26, Chemicon®, from mouse

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

VI-26, monoclonal

species reactivity

human, rabbit

should not react with

rat

manufacturer/tradename

Chemicon®

availability

not available in Japan

technique(s)

ELISA: suitable
immunohistochemistry: suitable (paraffin)

isotype

IgG1κ

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... COL6A1(1291)

Other Notes

浓度:请参考批次特异性浓缩物的分析证书。

Physical form

形式:纯化
液体溶于0.1 M磷酸钠缓冲液,pH值7.0含有2%无蛋白酶的牛血清白蛋白。
纯化的蛋白 A

Analysis Note

对照
睾丸,结缔组织

Application

丙酮固定石蜡包埋组织的免疫组化。不建议福尔马林固定。 抗原回收在非特异性过氧化物酶阻断前用0.04%胰蛋白酶在0.01 M CaCl(2)0.05 M Tris-HCL pH值7.6,37°C中处理10分钟。

EIA

最佳工作稀释度必须由最终用户确定。
已发表抗VI型胶原抗体,克隆VI-26可检测VI&型胶原水平,&经验证可用于ELISA,IH(P)。
研究子类别
ECM 蛋白
研究类别
细胞结构

Biochem/physiol Actions

与hCL(VI)发生特异性反应。 这是抗人VI型胶原的纯化小鼠单克隆抗体。VI-26不与变性或还原的VI型胶原反应,尽管该抗体确实识别由α1(VI),α2(VI)α3(γ)组成的三螺旋。 表位尚未定位,并且已知单克隆抗体在天然测定中不会与胶原I、II、III、IV或V反应。

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

Preparation Note

自发运之日起在-20°C可保存1年。等分以避免反复冻融。为了最大程度地回收产品,在融化后和取下盖子之前,将原始样品瓶进行离心。

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

未找到合适的产品?  

试试我们的产品选型工具.

存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Tiziana Triulzi et al.
PloS one, 8(2), e56761-e56761 (2013-02-27)
We recently showed that differential expression of extracellular matrix (ECM) genes delineates four subgroups of breast carcinomas (ECM1, -2, -3- and -4) with different clinical outcome. To further investigate the characteristics of ECM signature and its impact on tumor progression
D O Visscher et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 107(5), 1711-1721 (2018-11-02)
The aim of this study was to design and manufacture an easily assembled cartilage implant model for auricular reconstruction. First, the printing accuracy and mechanical properties of 3D-printed poly-ε-caprolactone (PCL) scaffolds with varying porosities were determined to assess overall material
Laura K Zamurs et al.
The Journal of biological chemistry, 290(7), 4272-4281 (2014-12-24)
Bethlem myopathy and Ullrich congenital muscular dystrophy (UCMD) sit at opposite ends of a clinical spectrum caused by mutations in the extracellular matrix protein collagen VI. Bethlem myopathy is relatively mild, and patients remain ambulant in adulthood while many UCMD
Russell J Butterfield et al.
PloS one, 12(12), e0189664-e0189664 (2017-12-16)
The collagen VI related muscular dystrophies (COL6-RD), Ullrich congenital muscular dystrophy (UCMD) and Bethlem myopathy (BM) are among the most common congenital muscular dystrophies and are characterized by distal joint laxity and a combination of distal and proximal joint contractures.
Laura Briñas et al.
Annals of neurology, 68(4), 511-520 (2010-10-27)
Mutations in the genes encoding the extracellular matrix protein collagen VI (ColVI) cause a spectrum of disorders with variable inheritance including Ullrich congenital muscular dystrophy, Bethlem myopathy, and intermediate phenotypes. We extensively characterized, at the clinical, cellular, and molecular levels

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持