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Merck
CN
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主要文件

MAB3301

Sigma-Aldrich

Anti-TIMP-1 Antibody, clone 147-6D11

clone 147-6D11, Chemicon®, from mouse

别名:

Tissue Inhibitor of Metalloproteinase-1

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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

mouse

质量水平

抗体形式

purified antibody

抗体产品类型

primary antibodies

克隆

147-6D11, monoclonal

种属反应性

human

制造商/商品名称

Chemicon®

技术

ELISA: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable

同位素/亚型

IgG1κ

NCBI登记号

UniProt登记号

运输

dry ice

靶向翻译后修饰

unmodified

基因信息

human ... TIMP1(7076)

特异性

The antibody specifically reacts with human TIMP-1. This is a purified mouse monoclonal antibody to recombinant human tissue inhibitor of metalloproteinases-1 (recombinant TIMP-1).

SPECIES REACTIVITY:

Does not cross-react with mouse and rat TIMP-1.

免疫原

Mouse Mac-1

应用

Immunoblotting: Suggested Dilution 1μg/mL

Immunohistochemistry on paraffin-embedded tissue sections using PLP fixation; not tested on traditional formalin fixed tissues. Antigen retrieval is HIER methods

ElA
This Anti-TIMP-1 Antibody, clone 147-6D11 is validated for use in ELISA, WB, IH(P) for the detection of TIMP-1.

联系

Replaces: MAB1338

外形

Format: Purified

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Marcia Riboldi et al.
Reproduction (Cambridge, England), 160(5), 673-684 (2020-10-17)
During embryo implantation, endometrial angiogenesis is regulated by signals originating from the endometrium itself and the developing embryo. It has been suggested that hCG may play a pro-angiogenic role; therefore, we sought to understand its regulatory role in blood vessel
A Tapia-Pizarro et al.
Human reproduction (Oxford, England), 28(8), 2215-2227 (2013-05-23)
Are secreted extracellular matrix (ECM) remodelling elements, relevant to embryo implantation and placentation, modified by hCG in endometrial stromal cells (ESCs)? hCG decreases tissue inhibitor of metalloproteinase 1 (TIMP-1) secretion in ESCs, thereby facilitating extravillous trophoblast invasion in vitro. Successful
Philipp Christian Seppelt et al.
PloS one, 11(2), e0148012-e0148012 (2016-02-04)
Marfan syndrome is an autosomal dominant inherited disorder of connective tissue. The vascular complications of Marfan syndrome have the biggest impact on life expectancy. The aorta of Marfan patients reveals degradation of elastin layers caused by increased proteolytic activity of

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