推荐产品
生物来源
mouse
质量水平
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
147-6D11, monoclonal
种属反应性
human
制造商/商品名称
Chemicon®
技术
ELISA: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable
同位素/亚型
IgG1κ
NCBI登记号
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
human ... TIMP1(7076)
特异性
The antibody specifically reacts with human TIMP-1. This is a purified mouse monoclonal antibody to recombinant human tissue inhibitor of metalloproteinases-1 (recombinant TIMP-1).
SPECIES REACTIVITY:
Does not cross-react with mouse and rat TIMP-1.
SPECIES REACTIVITY:
Does not cross-react with mouse and rat TIMP-1.
免疫原
Mouse Mac-1
应用
Immunoblotting: Suggested Dilution 1μg/mL
Immunohistochemistry on paraffin-embedded tissue sections using PLP fixation; not tested on traditional formalin fixed tissues. Antigen retrieval is HIER methods
ElA
Immunohistochemistry on paraffin-embedded tissue sections using PLP fixation; not tested on traditional formalin fixed tissues. Antigen retrieval is HIER methods
ElA
This Anti-TIMP-1 Antibody, clone 147-6D11 is validated for use in ELISA, WB, IH(P) for the detection of TIMP-1.
联系
Replaces: MAB1338
外形
Format: Purified
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Reproduction (Cambridge, England), 160(5), 673-684 (2020-10-17)
During embryo implantation, endometrial angiogenesis is regulated by signals originating from the endometrium itself and the developing embryo. It has been suggested that hCG may play a pro-angiogenic role; therefore, we sought to understand its regulatory role in blood vessel
Human reproduction (Oxford, England), 28(8), 2215-2227 (2013-05-23)
Are secreted extracellular matrix (ECM) remodelling elements, relevant to embryo implantation and placentation, modified by hCG in endometrial stromal cells (ESCs)? hCG decreases tissue inhibitor of metalloproteinase 1 (TIMP-1) secretion in ESCs, thereby facilitating extravillous trophoblast invasion in vitro. Successful
PloS one, 11(2), e0148012-e0148012 (2016-02-04)
Marfan syndrome is an autosomal dominant inherited disorder of connective tissue. The vascular complications of Marfan syndrome have the biggest impact on life expectancy. The aorta of Marfan patients reveals degradation of elastin layers caused by increased proteolytic activity of
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