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生物来源
mouse
质量水平
偶联物
ALEXA FLUOR™ 488
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
A2B5-105 (7), monoclonal
种属反应性
mouse, chicken, human, rat
制造商/商品名称
Chemicon®
技术
immunocytochemistry: suitable
immunohistochemistry: suitable
同位素/亚型
IgM
运输
wet ice
靶向翻译后修饰
unmodified
特异性
The antibody recognizes an epitope common to silaogangliosides and sulfatides from the plasma membranes of neurons, and neuroendocrine and glial cells. Anti-A2B5 has been used to specifically stain:
· Neurofibrillary tangles in the post-mortem brain tissue of patients with a confirmed diagnosis of Alzheimer′s disease (Majocha et al., 1989)
· Neurons of chicken retina, brain, spinal cord, and dorsal root ganglia (Schnitzer & Schachner, 1982; Eisenbarth et al., 1979.
· Rat striatal nerve terminals [synaptosomes (Wolf & Kapatos, 1989].
· Neuroblastoma cells in man (Oppedal et al., 1989; Coakham et al., 1985).
· Rat insulinoma cells and pancreatic islets cells (Shimizu et al., 1983; Bartholomeusz et al., 1989).
· Human and rat thymic epithelial cells (Haynes, et al., 1988).
· Cells involved in gliogenesis (Bottenstein et al., 1988; Suzumura & slerberg, 1989).
· Oligodendrocytes and astrocytes, type II (Dubois-Dalcq et al., 1990).
· Neurofibrillary tangles in the post-mortem brain tissue of patients with a confirmed diagnosis of Alzheimer′s disease (Majocha et al., 1989)
· Neurons of chicken retina, brain, spinal cord, and dorsal root ganglia (Schnitzer & Schachner, 1982; Eisenbarth et al., 1979.
· Rat striatal nerve terminals [synaptosomes (Wolf & Kapatos, 1989].
· Neuroblastoma cells in man (Oppedal et al., 1989; Coakham et al., 1985).
· Rat insulinoma cells and pancreatic islets cells (Shimizu et al., 1983; Bartholomeusz et al., 1989).
· Human and rat thymic epithelial cells (Haynes, et al., 1988).
· Cells involved in gliogenesis (Bottenstein et al., 1988; Suzumura & slerberg, 1989).
· Oligodendrocytes and astrocytes, type II (Dubois-Dalcq et al., 1990).
免疫原
Embryonic chicken retinal cells
应用
Anti-Neuron Cell Surface Antigen Antibody, clone A2B5-105 (7), Alexa Fluor 488 detects level of Neuron Cell Surface Antigen & has been published & validated for use in IC, IH.
Immunocytochemistry
Immunohistochemistry: 1:30
Optimal working dilutions must be determined by end user.
Immunohistochemistry: 1:30
Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neuronal & Glial Markers
Neuronal & Glial Markers
外形
Purified immunoglobulin conjugated to Alexa Fluor™ 488. Liquid in Phosphate buffer with 15 mg/mL BSA as a stabilizer and 0.1% sodium azide.
储存及稳定性
Maintain at 2-8°C in undiluted aliquots in the dark for up to 6 months after date of receipt.
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
ALEXA FLUOR is a trademark of Life Technologies
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Alexa Fluor™ is a registered trademark of Molecular Probes, Inc.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Frontiers in nutrition, 9, 1054431-1054431 (2022-11-29)
During early neurodevelopment of infant, myelination plays an essential role in brain connectivity and emergence of behavioral and cognitive function. Early life nutrition is an important factor to shape myelination and consequently cognitive appearance. To analyze the effects of additive
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