MAB2300
Milli-Mark® 泛神经元标志物
Milli-Mark Pan Neuronal Marker is an antibody targeting the Pan Neuronal Marker protein, validated for use in ICC, IHC, IF & IHC.
别名:
神经元标记
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
monoclonal
Species reactivity:
rat, mouse, human
Application:
immunocytochemistry
immunofluorescence
immunohistochemistry (formalin-fixed, paraffin-embedded sections)
immunofluorescence
immunohistochemistry (formalin-fixed, paraffin-embedded sections)
Technique(s):
immunocytochemistry: suitable
immunofluorescence: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
immunofluorescence: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
Citations:
33
产品名称
Milli-Mark® 泛神经元标志物, Milli-Mark Pan Neuronal Marker is an antibody targeting the Pan Neuronal Marker protein, validated for use in ICC, IHC, IF & IHC.
biological source
mouse
antibody form
purified antibody
clone
monoclonal
species reactivity
rat, mouse, human
manufacturer/tradename
Neuro-Chrom
technique(s)
immunocytochemistry: suitable
immunofluorescence: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
isotype
IgG1
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
相关类别
Analysis Note
对照
Rat E18皮层原代神经元
Rat E18皮层原代神经元
通过免疫细胞化学法对大鼠E18皮层原代神经元进行了常规评估
Application
研究子类别
神经 & 胶质标记
神经 & 胶质标记
研究类别
神经科学
神经科学
Biochem/physiol Actions
与其他物种的反应性尚未确定。
货号# MAB2300 对轴突（神经突）、树突、细胞核和神经元的细胞体有特异性。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
神经元蛋白的抗体已经成为关键工具，可识别神经元并辨别培养物和复杂组织的形态学特征。 尽管经典组织学技术（如高尔基体染色）和现代分子生物学方法（如GFP 构建物）的标记可以得到良好的细胞结构细节，对于许多神经科学研究领域的需求而言，这些方法技术困难并且不实用。神经元特异性抗体是便捷、精确、有用的工具，可以揭示细胞结构，但是仅限于神经元内部的蛋白靶标分布，这种分布从细胞核到体细胞再到树突和轴突可能有很大区别。 为了得到尽可能完整的涵盖神经元所有部分的形态学染色，Millipore 开发了一种单克隆抗体混合物，这种混合物与泛神经元结构中分布的关键体细胞、细胞核、树突和轴突蛋白反应，采用单一的二抗即可检测。该抗体混合物在多种固定方法、细胞培养物和免疫组化方案中得到验证，包括脑组织，为研究人员研究神经元形态学，提供了一种便捷的特异性定性和定量工具。
Immunogen
表位：全神经元标志物
Physical form
含 0.05％ NaN3 的 PBS 中的单克隆抗体混合物
形式：纯化
Preparation Note
自收到之日起，在2-8°C下可稳定保存1年。
Legal Information
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Short-term fasting induces profound neuronal autophagy.
Alirezaei, M; Kemball, CC; Flynn, CT; Wood, MR; Whitton, JL; Kiosses, WB
Autophagy null
Harald Lund et al.
Nature immunology, 19(5), 1-7 (2018-04-18)
The cytokine transforming growth factor-β (TGF-β) regulates the development and homeostasis of several tissue-resident macrophage populations, including microglia. TGF-β is not critical for microglia survival but is required for the maintenance of the microglia-specific homeostatic gene signature1,2. Under defined host
Erdinç Dursun et al.
PloS one, 12(11), e0188605-e0188605 (2017-11-28)
Our recent study indicated that vitamin D and its receptors are important parts of the amyloid processing pathway in neurons. Yet the role of vitamin D receptor (VDR) in amyloid pathogenesis is complex and all regulations over the production of
Megan N Evilsizor et al.
Journal of visualized experiments : JoVE, (99), e52293-e52293 (2015-05-21)
Immunohistochemistry is a widely used technique for detecting the presence, location, and relative abundance of antigens in situ. This introductory level protocol describes the reagents, equipment, and techniques required to complete immunohistochemical staining of rodent brain tissue, using markers for
Erdinç Dursun et al.
Noro psikiyatri arsivi, 51(2), 163-168 (2014-06-01)
Neurodegeneration is a process that is characterized by the loss of neuronal structure and function and eventually ends with neuronal death. An elevated level of inducible nitric oxide synthase (iNOS) is suggested to accompany this process by inducing oxidative and
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