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Merck
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主要文件

MAB2146Z

Sigma-Aldrich

Anti-ICAM-1 Antibody, clone P2A4, Azide Free

clone P2A4, Chemicon®, from mouse

别名:

CD54, MAB2146

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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

mouse

质量水平

抗体形式

purified antibody

抗体产品类型

primary antibodies

克隆

P2A4, monoclonal

种属反应性

human

制造商/商品名称

Chemicon®

技术

ELISA: suitable
flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable

同位素/亚型

IgG1

NCBI登记号

UniProt登记号

运输

dry ice

靶向翻译后修饰

unmodified

基因信息

human ... ICAM1(3383)

特异性

Human ICAM-1

免疫原

IL-1beta activated HUVEC (human)

应用

Immunohistochemistry: for use on acetone or paraformaldehyde fixed tissue

Immunocytochemistry: for use on B cells, PBL, T cells

Immunoprecipitation

FACS

ELISA

Inhibits ICAM-1 dependent adhesive interactions

Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Research Sub Category
Adhesion (CAMs)
This Anti-ICAM-1 Antibody, clone P2A4, Azide Free is validated for use in ELISA, FC, IP, IC, IH, FUNC for the detection of ICAM-1.

外形

Format: Purified
Sterile-filtered lquid containing 0.2M phosphate buffer, 0.25M sodium chloride, no preservatives.

储存及稳定性

Maintain at -20°C.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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LFA-1 and ICAM-1 expression induced during melanoma-endothelial cell co-culture favors the transendothelial migration of melanoma cell lines in vitro.
Ghislin, S; Obino, D; Middendorp, S; Boggetto, N; Alcaide-Loridan, C; Deshayes, F
BMC Cancer null
Kelly M Bailey et al.
Oncotarget, 10(36), 3385-3399 (2019-06-06)
Metastatic and relapsed Ewing sarcoma typically afflicts the adolescent population and is largely fatal. These bone tumors are most commonly driven by the fusion oncoprotein EWS-FLI1. Ewing tumors demonstrate significant intra-tumoral heterogeneity, and individual tumor cells can express highly variable
Mario C Manresa et al.
Gastroenterology, 159(5), 1778-1792 (2020-07-28)
Eosinophilic esophagitis (EoE) is an antigen-mediated eosinophilic disease of the esophagus that involves fibroblast activation and progression to fibrostenosis. Cytokines produced by T-helper type 2 cells and transforming growth factor beta 1 (TGFβ1) contribute to the development of EoE, but

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