推荐产品
生物来源
mouse
质量水平
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
P2A4, monoclonal
种属反应性
human
制造商/商品名称
Chemicon®
技术
ELISA: suitable
flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
同位素/亚型
IgG1
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... ICAM1(3383)
特异性
Human ICAM-1
免疫原
IL-1beta activated HUVEC (human)
应用
Anti-ICAM-1 Antibody, clone P2A4 is an antibody against ICAM-1 for use in ELISA, FC, IP, IC, IH.
Immunohistochemistry: for use on acetone or paraformaldehyde fixed tissue
Immunocytochemistry: for use on B cells, PBL, T cells
Immunoprecipitation
FACS
ELISA
Inhibits ICAM-1 dependent adhesive interactions
Optimal working dilutions must be determined by end user.
Immunocytochemistry: for use on B cells, PBL, T cells
Immunoprecipitation
FACS
ELISA
Inhibits ICAM-1 dependent adhesive interactions
Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Adhesion (CAMs)
Adhesion (CAMs)
外形
Format: Purified
Nonsterile liquid contains 0.2M phosphate buffer, 0.25M sodium chloride, and 0.1% sodium azide. Filtered through a 0.45 micron membrane filter.
储存及稳定性
Maintain at +2-8°C.
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Alba Carmona et al.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 19(10), 1439-1445 (2013-07-13)
Endothelial dysfunction seems to be a key factor in the development of several complications observed early after hematopoietic stem cell transplantation (HSCT). The conditioning regimen and many other factors associated with the procedure are responsible for this endothelial damage. The
Qiangjun Cai et al.
Arteriosclerosis, thrombosis, and vascular biology, 24(12), 2263-2270 (2004-10-02)
Vascular smooth muscle cells (VSMCs) may regulate monocyte functions within atherosclerotic lesions. We investigated the impact of VSMC/monocyte interactions on monocyte apoptosis and scavenger receptor CD36 expression, key events related to monocyte survival and differentiation. Serum deprivation significantly increased THP-1
Akio Kawakami et al.
Circulation, 114(7), 681-687 (2006-08-09)
Activation of vascular endothelial cells (ECs) plays an important role in atherogenesis and plaque instability. Lipoproteins containing apolipoprotein CIII (apoCIII) predict coronary heart disease (CHD). We recently reported that apoCIII has a proinflammatory effect on human monocytes. In this study
João M Furtado et al.
Immunology and cell biology, 90(9), 912-915 (2012-04-25)
Retinal infection is the most common clinical manifestation of toxoplasmosis. The route by which circulating Toxoplasma gondii tachyzoites cross the vascular endothelium to enter the human retina is unknown. Convincing studies using murine encephalitis models have strongly implicated leukocyte taxis
E Pluskota et al.
The Journal of biological chemistry, 275(39), 30029-30036 (2000-06-24)
Intercellular adhesion molecule-1 (ICAM-1) binds to the plasma protein fibrinogen (Fg) to mediate leukocyte/endothelial cell interactions. In our studies, the ligation of Fg to ICAM-1 on tumor necrosis factor-alpha-stimulated endothelial cells resulted in the tyrosine phosphorylation of Src homology domain
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