推荐产品
生物来源
mouse
质量水平
抗体形式
ascites fluid
抗体产品类型
primary antibodies
克隆
P4G9, monoclonal
种属反应性
human
制造商/商品名称
Chemicon®
技术
immunohistochemistry: suitable
同位素/亚型
IgG2bκ
NCBI登记号
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
human ... ITGA4(3676)
特异性
Human integrin alpha4. The alpha4beta1 integrin receptor recognizes an RGD-independent alternative adhesion site in the CS-1 region of fibronectin.
应用
Detect Integrin α4 using this Anti-Integrin α4 Antibody, clone P4G9 validated for use in IH.
Immunocytochemistry on Jurkat cells at 1:1,600.
Inhibits attachment of hematopoeitic cells and fibroblasts to fibronectin (note: sodium azide should be removed prior to attachment assay).
Optimal working dilutions must be determined by the end user.
Inhibits attachment of hematopoeitic cells and fibroblasts to fibronectin (note: sodium azide should be removed prior to attachment assay).
Optimal working dilutions must be determined by the end user.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Integrins
Integrins
联系
Replaces: 04-1131
储存及稳定性
Store at -20 °C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
A New alpha5beta1 integrin-dependent survival pathway through GSK3beta activation in leukemic cells.
Fabienne De Toni-Costes et al.
PloS one, 5(3), e9807-e9807 (2010-03-31)
Cell survival mediated by integrin engagement has been implicated in cell adhesion-mediated drug resistance. We have recently demonstrated that the activation of glycogen synthase kinase 3 beta (GSK3beta) is a new pathway supporting the chemoresistance of leukemic cells adhered to
Barbara Garmy-Susini et al.
The Journal of clinical investigation, 115(6), 1542-1551 (2005-05-20)
Neovascularization depends on vascular cell proliferation and on the stabilization of vessels by association of vascular smooth muscle-like pericytes with ECs. Here we show that integrin alpha4beta1 (VLA-4) and VCAM-1 promote close intercellular adhesion between ECs and pericytes and that
Ming-Yi Lee et al.
PloS one, 4(10), e6913-e6913 (2009-10-23)
Human placental multipotent mesenchymal stromal cells (hPMSCs) can be isolated from term placenta, but their angiogenic ability and the regulatory pathways involved are not known. hPMSCs were shown to express integrins alpha(v), alpha(4), alpha(5), beta(1), beta(3), and beta(5) and could
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