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Merck
CN
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文件

MAB1919

Sigma-Aldrich

抗原纤蛋白抗体，克隆11C1.3

clone 11C1.3, Chemicon®, from mouse

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别名:
Anti-ACMICD, Anti-FBN, Anti-GPHYSD2, Anti-MASS, Anti-MFLS, Anti-MFS1, Anti-OCTD, Anti-SGS, Anti-SSKS, Anti-WMS, Anti-WMS2
UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

mouse

质量水平

100

抗体形式

purified antibody

抗体产品类型

primary antibodies

克隆

11C1.3, monoclonal

种属反应性

bovine, pig, human

制造商/商品名称

Chemicon®

技术

ELISA: suitable
immunofluorescence: suitable
immunohistochemistry: suitable (paraffin)
immunoprecipitation (IP): suitable
western blot: suitable

同位素/亚型

IgG1κ

NCBI登记号

NM_000138.3

UniProt登记号

P35555

运输

dry ice

靶向翻译后修饰

unmodified

基因信息

human ... FBN1(2200)

特异性

牛带状原纤维。与人弹性蛋白微原纤维反应良好，可用于马凡氏患者或从这些患者获得的成纤维细胞中研究这些原纤维的存在和组织。

免疫原

牛带状原纤维

应用

免疫印迹：抗体与牛主动脉平滑肌细胞释放的35万Da蛋白反应，该蛋白与原纤维蛋白相同。

免疫组化：新鲜冷冻组织：1:200-1:500。石蜡切片经微波柠檬酸盐缓冲液抗原提取后有反应。

免疫沉淀：5微升抗体稀释在不超过400微升的牛平滑肌细胞浓缩上清液中。我们建议使用抗小鼠IgG抗体头或兔抗小鼠捕获抗体，然后使用蛋白A。A.

ELISA

最佳稀释度必须由最终用户确定。
抗纤原蛋白抗体，克隆11C1.3是用于ELISA、IF、IP、WB、IH(P)的抗纤原蛋白抗体。
研究子类别
ECM 蛋白
研究类别
细胞结构

外形

形式：纯化
液体

储存及稳定性

以未稀释的等分试样保存于-20°C下12个月。应避免反复冻/融循环。

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

WGK

nwg

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ADAMTS10 protein interacts with fibrillin-1 and promotes its deposition in extracellular matrix of cultured fibroblasts.
Kutz, WE; Wang, LW; Bader, HL; Majors, AK; Iwata, K; Traboulsi, EI; Sakai, LY; Keene, DR; Apte, SS
The Journal of Biological Chemistry null
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Latent transforming growth factor-beta-1 binding protein-2 (LTBP-2) is a protein of ill-defined function associated with elastic fibers during elastinogenesis. Although LTBP-2 binds fibrillin-1, fibulin-5, and heparin/heparan sulfate, molecules critical for normal elastic fiber assembly, it does not interact directly with
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