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产品名称
Anti-Vimentin Antibody, clone LN-6, culture supernatant, clone LN-6, Chemicon®
生物来源
mouse
质量水平
抗体形式
culture supernatant
抗体产品类型
primary antibodies
克隆
LN-6, monoclonal
种属反应性
human, mouse
制造商/商品名称
Chemicon®
技术
immunohistochemistry: suitable (paraffin)
同位素/亚型
IgM
NCBI登记号
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
human ... VIM(7431)
一般描述
Vimentin is a class III intermediate filament protein (homopolymers) found in various non-epithelial cells including mesenchymal cells and fibroblasts. In many cells of mesenchymal origin, it is one of the most prominent phosphoproteins, especially during cell division when enhanced phosphorylation of vimentin corresponds with the reorganization of vimentin filaments.
特异性
Reacts with human mesenchymal cells and derived sarcomas. Reacts with an epitope of the cytoskeletal protein vimentin but unlike other vimentin antibodies, does not react with human lymphoid cells or derived malignancies. Reactive with endothelium, muscle, fibroblasts, melanocytes, peripheral nerve, sertoli cells, kidney mesangial cells and tubules, osteoblasts and periosteum, non-hematopoietic tumors of mesenchymal origin (all sarcomas), meningiomas and melanomas.
免疫原
Nuclei from adult human thymic biopsy specimens.
应用
Anti-Vimentin Antibody, clone LN-6 detects level of Vimentin & has been published & validated for use in IH(P).
Immunohistochemistry on B5 fixed, paraffin embedded tissue sections.
目标描述
57-60 kDa
外形
Liquid tissue culture supernatant containing 0.02% sodium azide.
分析说明
Control
Hyperplastic lymph nodes.
Hyperplastic lymph nodes.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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