推荐产品
生物来源
mouse
质量水平
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
H1, monoclonal
种属反应性
rat, human, bovine
制造商/商品名称
Chemicon®
技术
ELISA: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
radioimmunoassay: suitable
western blot: suitable
同位素/亚型
IgG1
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... KIF5B(3799)
特异性
与非神经元 KHC的重链N末端附近的的主要形式反应。
免疫原
表位：重链，非神经元KHC
应用
在多聚甲醛固定的组织上进行免疫组化。也适用于EM。
免疫细胞化学：多聚甲醛固定的细胞； 5-10′ RT，新鲜制备的4% PFA；以 0.1-.2% triton X-100透化的3% 正常血清封闭缓冲液
免疫印迹：识别非神经元样品的 124kDa KHC
免疫沉淀
驱动蛋白介导的转运的抑制
EIA/RIA
最佳工作稀释度必须由最终用户进行确定。
免疫细胞化学：多聚甲醛固定的细胞； 5-10′ RT，新鲜制备的4% PFA；以 0.1-.2% triton X-100透化的3% 正常血清封闭缓冲液
免疫印迹：识别非神经元样品的 124kDa KHC
免疫沉淀
驱动蛋白介导的转运的抑制
EIA/RIA
最佳工作稀释度必须由最终用户进行确定。
抗驱动蛋白抗体（重链，非神经元KHC，克隆H1）可检测驱动蛋白水平 & 已有相关文献发表 & 经验证可用于ELISA、IP、RIA、WB、IC、IH。
外形
形式：纯化
液体形式，溶于0.02 M磷酸盐缓冲液、0.25 M NaCl（pH 7.6）和0.1%叠氮化钠中。
其他说明
浓度：请参考批次特异性浓缩物的检验报告。
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Sten Strunze et al.
Cell host & microbe, 10(3), 210-223 (2011-09-20)
Many viruses deliver their genomes into the host cell nucleus for replication. However, the size restrictions of the nuclear pore complex (NPC), which regulates the passage of proteins, nucleic acids, and solutes through the nuclear envelope, require virus capsid uncoating
Hongtao Chen et al.
Biophysical journal, 94(4), 1508-1520 (2007-11-06)
The role of cholesterol in the regulation of endosome motility was investigated by monitoring the intracellular trafficking of endocytosed folate receptors (FRs) labeled with fluorescent folate conjugates. Real-time fluorescence imaging of HeLa cells transfected with green fluorescent protein-tubulin revealed that
Wen-Jun Wang et al.
Drug metabolism and disposition: the biological fate of chemicals, 42(1), 62-69 (2013-10-12)
Previous studies identified a family of organic anion transport proteins (OATPs), many of which have C-terminal PDZ binding consensus sequences. In particular, the C-terminal four amino acids of Oatp1a1, a transporter on rat and mouse hepatocytes, comprise a consensus binding
Souvik Sarkar et al.
Traffic (Copenhagen, Denmark), 7(8), 1078-1091 (2006-06-01)
Intracellular trafficking regulates the abundance and therefore activity of transporters present at the plasma membrane. The transporter, Na+-taurocholate co-transporting polypeptide (ntcp), is increased at the plasma membrane upon treatment of cells with cAMP, for which microtubules (MTs) are required and
Jie Zhou et al.
PLoS pathogens, 14(5), e1007055-e1007055 (2018-05-22)
Many viruses, including adenovirus, exhibit bidirectional transport along microtubules following cell entry. Cytoplasmic dynein is responsible for microtubule minus end transport of adenovirus capsids after endosomal escape. However, the identity and roles of the opposing plus end-directed motor(s) remain unknown.
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