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Merck
CN

MAB1522

Anti-Actin Antibody, smooth muscle γ & α actin,

CHEMICON®, mouse monoclonal, CGA7

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关于此项目

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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产品名称

Anti-Actin Antibody, smooth muscle γ & α actin, clone CGA7, ascites fluid, clone CGA7, Chemicon®

Quality Level

biological source

mouse

antibody form

ascites fluid

clone

CGA7, monoclonal

species reactivity

human, rat, chicken, rabbit, monkey

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable

isotype

IgG2a

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Application

Detect Actin using this Anti-Actin Antibody, smooth muscle γ & α actin, clone CGA7 validated for use in WB, IH, IH(P).
Western Blot: 1:1000 (approximately 43 kDa)

Immunohistochemistry (paraffin, formalin, deparaffinized methacarn-fixed tissue: 1:10,000 or alcohol fixation)

Optimal dilutions must be determined by the end user.

Biochem/physiol Actions

Antibody recognizes actin isotypes alpha and gamma of smooth muscle cells, but not skeletal or cardiac muscle cells. Reactive with myoepithelium, but nonreactive with other mesenchymal and all epithelial cells. The antibody labels eiomyosarcomas and leiomyomas but does not react with other neoplasms such as carcinomas or lymphoma.

Immunogen

Chicken gizzard actin
Epitope: smooth muscle gamma & alpha actin

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Liang Chen et al.
Journal of cardiovascular pharmacology, 68(3), 215-222 (2016-04-26)
The cardiotonic pill (CP), consisting of a mixture of Radix Salviae Miltiorrhizae, Radix Notoginseng, and Borneolum Syntheticum, has been widely used in the prevention and treatment of cardiovascular disease. Adhesion molecules, including intercellular cell adhesion molecule-1 and vascular cell adhesion
Xin Yao et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 13(1), 161-169 (2007-01-04)
Intratumoral microvascular density (MVD) has been controversial as an indicator of prognosis in clear cell renal cell carcinoma (CCRCC). Classification of the intratumoral blood vessels based on differential expressions of blood vessel markers has not been correlated with patient prognosis
Cultured circular smooth muscle from the rabbit colon.
Kao, H W, et al.
In Vitro Cellular & Developmental Biology, 24, 787-794 (1988)
Functional expression of the GABAB receptor in human airway smooth muscle.
Osawa, Y; Xu, D; Sternberg, D; Sonett, JR; D'Armiento, J; Panettieri, RA; Emala, CW
American Journal of Physiology. Lung Cellular and Molecular Physiology null
Mary E Donohoe et al.
Molecular cell, 25(1), 43-56 (2007-01-16)
In mammals, inactivation of one X chromosome in the female equalizes gene dosages between XX females and XY males. Two noncoding loci, Tsix and Xite, together regulate X chromosome fate by controlling homologous chromosome pairing, counting, and mutually exclusive choice.

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