MAB10404
Anti-Ghrelin Antibody, clone 1ML-1D7
ascites fluid, clone 1ML-1D7, from mouse
别名:
ghrelin/obestatin prepropeptide1, ghrelin/obestatin2, ghrelin, growth hormone secretagogue receptor ligand1, obestatin1, ghrelin/obestatin preprohormone, Motilin-related peptide2, ghrelin1, M46 protein3, Growth hormone secretagogue
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About This Item
推荐产品
生物来源
mouse
质量水平
抗体形式
ascites fluid
抗体产品类型
primary antibodies
克隆
1ML-1D7, monoclonal
种属反应性
mouse, human
技术
immunocytochemistry: suitable
western blot: suitable
同位素/亚型
IgG1κ
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... GHRL(51738)
一般描述
Ghrelin is a 28 amino acids peptide with an essential n-octonayl modification at Serine 3. This peptide hormone is known as an endogenous ligand for the growth hormone secretagogue receptor and shares sequence similarity with the peptide hormone Motilin. Ghrelin displays pleotropic actions including growth hormone secretion, feeding behaviour and gastrointestinal motility. It is predominantly produced by enteroendocrine cells from the gastrointestinal tract, but has been shown to play a significant role in neurotrophy, particularly in the hippocampus, and appears to be essential for cognitive adaptation to changing environments and the process of learning.
特异性
This antibody recognizes Ghrelin at the N-terminus.
免疫原
Linear Peptide corresponding to the N-terminus of human Ghrelin.
应用
Detect Ghrelin using this Anti-Ghrelin Antibody, clone 1ML-1D7 validated for use in WB & IC.
Immunocytochemistry Analysis: A 1:500 dilution from a previous lot detected Ghrelin in A431 cells.
质量
Evaluated by Western Blot in mouse stomach tissue lysate.
Western Blot Analysis: A 1:1,000 dilution of this antibody detected Ghrelin in 10 µg of mouse stomach tissue lysate.
Western Blot Analysis: A 1:1,000 dilution of this antibody detected Ghrelin in 10 µg of mouse stomach tissue lysate.
目标描述
13 kDa calculated and observed
分析说明
Control
Mouse stomach tissue lysate
Mouse stomach tissue lysate
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
Gene therapy, 31(3-4), 165-174 (2024-01-05)
Ghrelin is commonly known as the 'hunger hormone' due to its role in stimulating food intake in humans. However, the roles of ghrelin extend beyond regulating hunger. Our aim was to investigate the ability of ghrelin to protect against hydrogen
Cell metabolism, 19(6), 927-940 (2014-05-06)
Orexin neuropeptides promote arousal, appetite, reward, and energy expenditure. However, whether orexin affects bone mass accrual is unknown. Here, we show that orexin functions centrally through orexin receptor 2 (OX2R) in the brain to enhance bone formation. OX2R null mice
Histopathologic and immunohistochemical sequelae of bariatric embolization in a porcine model.
Journal of Vascular and Interventional Radiology : Jvir null
International journal of clinical and experimental pathology, 8(12), 15993-15999 (2016-02-18)
Maternal stress exerts long-lasting postnatal growth on offspring, which persist into adulthood. However, the effect of maternal stress on appetizing system has not been widely reported. In this study, we found that maternal immobilization stress (IS) during lactation resulted in
Cells, 10(11) (2021-11-28)
Background: Although several approaches have revealed much about individual factors that regulate pancreatic development, we have yet to fully understand their complicated interplay during pancreas morphogenesis. Gfi1 is transcription factor specifically expressed in pancreatic acinar cells, whose role in pancreas
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