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IL038

Sigma-Aldrich

白细胞介素-1β蛋白,重组人类

The recombinant human Interleukin-1beta protein (or IL-1beta protein) is a potent immuno-modulator which mediates a wide range of immune & inflammatory responses including the activation of B & T-cells.

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别名:
IL-1beta
UNSPSC代码:
12352202
eCl@ss:
32160405
NACRES:
NA.75

生物来源

human

质量水平

检测方案

>98% (SDS-PAGE and HPLC)

比活

>1 x 10e9 U/mg

制造商/商品名称

Chemicon®

技术

cell culture | mammalian: suitable

杂质

<0.1 ng/μg endotoxin (of human IL-1beta; 1EU/μg)

输入

sample type hematopoietic stem cell(s)

NCBI登记号

UniProt登记号

运输

dry ice

一般描述

白细胞介素-1 β(或IL-1β蛋白)是一种有效的免疫调节剂,介导广泛的免疫和炎症反应,包括B和T细胞的激活。人IL-1β是一个17.3 kDa的蛋白质,含有153个氨基酸残基。

应用

对于大多数体外应用,人IL-1β在0.1至10.0 ng/mL.的浓度范围内发挥其生物学活性。响应细胞包括(部分列表): 白血球

外形

由10 mM Tris、pH 8.2无菌过滤和冻干,不含防腐剂。

储存及稳定性

冻干人IL-1β尽管在室温下稳定,但最好在-20°C下干燥保存。 快速离心后,在水中重溶至0.1-1.0 mg/mL的浓度。可以将该溶液稀释到其他缓冲溶液中。复溶的人IL-1β应该以未稀释的等分试样储存于 -20°C,最多保存六个月。

分析说明

比活度:与标准品相比,Chemicon人IL-1β具有完全的生物活性。通过剂量依赖性刺激鼠类D10S细胞测定的ED(50)为<0.001 ng/mL

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的人类或动物食用或应用。

WGK

WGK 1


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