产品名称
MILLIPLEX® Human Soluble Cytokine Receptor Panel,
description
Bulk (Space Saver) Premixed Human Soluble Cytokine Receptor 14-Plex Panel
Quality Level
species reactivity
human
packaging
pkg of 1 ea
manufacturer/tradename
Milliplex®
technique(s)
multiplexing: suitable
input
plasma
cell culture supernatant(s)
serum
assay range
sensitivity: 4-208 pg/mL
(Overnight Incubation minDC), standard curve range: 12.2-50,000 pg/mL
(sIL-4R, sIL-6R, sRAGE, sTNFRI, sTNFRII), standard curve range: 122.1-500,000 pg/mL
(sEGFR, sIL-1RII, sVEGF-R1, sVEGF-R2, sVEGF-R3), standard curve range: 24.4-100,000 pg/mL
(sCD30, sgp130, sIL-1RI, sIL-2Rα), inter-assay cv: <15%
intra-assay cv: <10%
detection method
fluorometric (Luminex® xMAP® technology)
shipped in
wet ice
storage temp.
2-8°C
General description
Cytokine receptors constitute an integral part of cytokine biology. Like cytokines, cytokine receptors are involved in normal physiological and pathological processes of almost all disease states. Soluble cytokine receptors naturally arise from genes encoding membrane- bound receptors or are direct derivatives of the receptors themselves. The discovery that soluble cytokine receptors are involved in regulating excessive inflammatory responses and modulating immune events has stimulated significant research interest in their potential role as immunotherapeutic agents. Many of these soluble cytokine receptors can inhibit the binding and biological activity of their cytokine ligands, making them very specific cytokine antagonists.
Application
MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 14 analytes in human serum, plasma, and cell culture supernatants.
Analytes included: sCD30, sEGFR, sGP130, sIL-1RI, sIL-1RII, sIL-2Rα, sIL-4R, sIL-6R, sRAGE, sTNFRI, sTNFRII, sVEGFR1, sVEGFR2, sVEGFR3
Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.
Analytes included: sCD30, sEGFR, sGP130, sIL-1RI, sIL-1RII, sIL-2Rα, sIL-4R, sIL-6R, sRAGE, sTNFRI, sTNFRII, sVEGFR1, sVEGFR2, sVEGFR3
Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.
Features and Benefits
- Cost-Efficient for Large Studies: Ideal for core labs or long-term projects requiring high sample throughput.
- Receptor-Ligand Interaction Profiling: Enables detailed analysis of cytokine signaling pathways and immune cell activation.
- Useful in Biomarker Discovery: Helps uncover novel receptor-based biomarkers for diagnostics and treatment monitoring.
- Reduced Packaging: Minimal packaging makes this option ideal for labs with limited space.
Legal Information
Luminex is a registered trademark of Luminex Corporation
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
For research use only. Not for use in diagnostic procedures.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
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