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HIGFBMAG-53K

Millipore

MILLIPLEX® 人IGF结合蛋白磁珠板 - 代谢多重分析

The Human IGF Binding Protein Panel, using the Luminex xMAP technology, enables the simultaneous analysis of 7 IGFBP protein biomarkers in human serum, plasma and cell culture samples.

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About This Item

UNSPSC代码:
12161503
eCl@ss:
32161000
NACRES:
NA.84

质量水平

200

种属反应性

human

制造商/商品名称

Milliplex®

assay range

accuracy: 79%
(IGFBP-5)
sensitivity: 0.01 ng/mL
(MinDC+2SD; IGFBP-1)
sensitivity: 0.07 ng/mL
(MinDC+2SD; IGFBP-7)
sensitivity: 0.12 ng/mL
(MinDC+2SD; IGFBP-6)
sensitivity: 0.15 ng/mL
(MinDC+2SD; IGFBP-3)
sensitivity: 0.96 ng/mL
(MinDC+2SD; IGFBP-4)
sensitivity: 1.09 ng/mL
(MinDC+2SD; IGFBP-2)
sensitivity: 9.87 ng/mL
(MinDC+2SD; IGFBP-5)
standard curve range: 0.03-25 ng/mL
(IGFBP-1)
standard curve range: 0.07-50  ng/mL
( IGFBP-3)
standard curve range: 0.07-50 ng/mL
(IGFBP-7)
standard curve range: 0.14-100 ng/mL
(IGFBP-6)
standard curve range: 0.34-250 ng/mL
(IGFBP-2)
standard curve range: 0.69-500 ng/mL
(IGFBP-4)
standard curve range: 1.37-1000 ng/mL
(IGFBP-5)
inter-assay cv: <15%
intra-assay cv: <10%
(IGFBP-1)
inter-assay cv: <15%
intra-assay cv: <10%
(IGFBP-2)
inter-assay cv: <15%
intra-assay cv: <10%
(IGFBP-3)
inter-assay cv: <15%
intra-assay cv: <10%
(IGFBP-4)
inter-assay cv: <15%
intra-assay cv: <10%
(IGFBP-5)
inter-assay cv: <15%
intra-assay cv: <10%
(IGFBP-6)
inter-assay cv: <15%
intra-assay cv: <10%
(IGFBP-7)

技术

multiplexing: suitable

检测方法

fluorometric (Luminex xMAP)

运输

wet ice

相关类别

一般描述

胰岛素样生长因子（IGF）结合蛋白（IGFBP）由多种组织和细胞表达，包括肝细胞。通过结合IGF-1和IGF-2，IGFBP在调节IGF作用，改变IGF与细胞表面受体的交互效应以及增加循环IGF半衰期和生物利用度中起关键作用。尽管尚未完全了解它们在细胞水平上的功能，但研究表明，根据所涉及的系统和所研究的IGFBP，它们具有刺激和抑制IGF-1活性的能力。IGFBP通过抑制IGF信号传导来调节细胞敏感性的能力可能在控制肿瘤细胞生长中起作用。

MILLIPLEX®人IGF结合蛋白（IGFBP）用于同时定量人血清、血浆和细胞全部条件培养基样本中以下的任何或所有分析物：IGFBP-1、IGFBP-2、IGFBP-3、IGFBP-4、IGFBP-5、IGFBP-6和IGFBP-7。该试剂盒采用96孔板，包含冻干标准混合物、两个内部检测质控品，可最多可测定38份样本，重复两次。

Luminex® xMAP®平台使用磁珠免疫分析格式，以实现理想的速度和灵敏度，同时定量多种分析物，从而显著提高生产力，同时节省宝贵的样本量。

面板类型：内分泌

特异性

交叉反应性
对于该面板中的一种分析物和任何其他分析物，抗体之间没有或有可以忽略不计的交叉反应性。

应用

  • 分析物：IGFBP-1、IGFBP-2、IGFBP-3、IGFBP-4、IGFBP-5、IGFBP-6和IGFBP-7
  • 推荐样本类型：人血清，血浆和细胞培养调节培养基
  • 推荐的样本稀释度：对于血清和血浆样品，当测定中不包括IGFBP3时，应使用每孔25 μL的1:25稀释液。当测定中包含IGFBP3时，使用1:200稀释液。组织培养上清液可以不稀释或用对照培养基进行适当稀释运行。
  • 分析运行时间：在2-8℃下过夜（16-20小时）。为了提高某些分析物的灵敏度，请在室温（20-25℃）下孵育2小时。
  • 研究类别：代谢
  • 研究子类别：代谢紊乱

特点和优势

通过在此面板中选择可用的分析物来设计多重试剂盒。

包装

96孔板
单个试剂盒即可满足您的所有需求。

储存及稳定性

试剂盒组分建议的存储温度为2-8°C。

其他说明

请联系技术服务部进行稀释度线性研究。

法律信息

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

象形图

Skull and crossbonesEnvironment
GHS06,GHS09

警示用语：

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

法规信息

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Fetal growth restriction is linked to adverse health outcomes and is prevalent in low- and middle-income countries; however, determinants of fetal growth are still poorly understood. The objectives were to determine the effect of prenatal vitamin D supplementation on the
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