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HCYP4MAG-64K

Millipore

MILLIPLEX® 人细胞因子/趋化因子磁珠板IV

The Human Inflammation / Immunology Bead-Based Multiplex Cytokine/Chemokine Assay kit IV, using the Luminex xMAP technology, enables the simultaneous analysis of 21 cytokine and chemokine biomarkers in human serum, plasma and cell culture samples.

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别名:
Human cytokine multiplex kit, Luminex® human cytokine immunoassay, Millipore human cytokine panel
UNSPSC代码:
12161503
eCl@ss:
32161000
NACRES:
NA.47

质量水平

200

种属反应性

human

制造商/商品名称

Milliplex®

assay range

accuracy: 101%
(BAFF/Blys)
accuracy: 101%
(BRAK/CSCL14)
accuracy: 101%
(IL-28B)
accuracy: 102%
(MPIF-1/CL23)
accuracy: 106%
(IL-19)
accuracy: 110%
(HCC-4/CCL16)
accuracy: 110%
(IL-34)
accuracy: 89%
(IL-32α)
accuracy: 95%
(IL-35)
accuracy: 99%
(IL-37)
sensitivity: 0.30 ng/mL
(YKL40/CHI3L1)
sensitivity: 0.8 ng/mL
(IL-24)
sensitivity: 0.8 ng/mL
(IL-35)
sensitivity: 0.9 ng/mL
(BAFF/BLyS)
sensitivity: 10.5 ng/mL
(HMGB1/HMG1)
sensitivity: 100.8 pg/mL
(CCL28)
sensitivity: 121.5 pg/mL
(IL-34)
sensitivity: 17.2 pg/mL
(IL-28B/IFN-λ3)
sensitivity: 248.2 pg/mL
sensitivity: 27.7 pg/mL
(IL-14/α-Taxilin)
sensitivity: 28.4 pg/mL
(HCC-4)
sensitivity: 3.5 pg/mL
(IL-36β)
sensitivity: 32.1 pg/mL
(IL-32α)
sensitivity: 33.2 pg/mL
(IL-38)
sensitivity: 375.6 pg/mL
(IFNβ)
sensitivity: 4.7 pg/mL
(CXCL16)
sensitivity: 5.2 pg/mL
(IL-37/IL-1F7)
sensitivity: 6.6 pg/mL
(MIP-4/PARC)
sensitivity: 607 pg/mL
(BRAK)
sensitivity: 7.8 pg/mL
(MPIF-1)
standard curve range: 0.1-100 ng/mL
(YKL40/CHI3L1)
standard curve range: 0.44-400 ng/mL
(BAFF/Blys)
standard curve range: 0.7-750 ng/mL
(IL-24)
standard curve range: 0.8-800 ng/mL
(IL-35)
standard curve range: 10-10,000 pg/mL
(MPIF-1/CL23)
standard curve range: 2-2,000 pg/mL
(IL-36β)
standard curve range: 2.0-2,000 ng/mL
(HMGB1)
standard curve range: 24-25,000 pg/mL
(IL-14)
standard curve range: 244-250,000 pg/mL
(IL-19)
standard curve range: 29-30,000 pg/mL
(IL-28B)
standard curve range: 3-3,000 pg/mL
(CXCL16)
standard curve range: 39-40,000 pg/mL
(IL-32α)
standard curve range: 488-500,000 pg/mL
(BRAK/CXCL14)
standard curve range: 488-500,000 pg/mL
(IFNβ)
standard curve range: 49-50,000 pg/mL
(IL-38)
standard curve range: 5-5,000 pg/mL
(IL-37)
standard curve range: 5-5,000 pg/mL
(MIP-4/PARC/CCL18)
standard curve range: 98-100,000 pg/mL
(CCL28)
standard curve range: 98-100,000 pg/mL
(IL-34)

技术

multiplexing: suitable

检测方法

fluorometric (Luminex xMAP)

运输

ambient

相关类别

一般描述

“细胞因子”是用于多种可溶性蛋白质和肽的通用术语，其在正常和病理条件下充当调节剂以调节单个细胞和组织的功能活性。这些蛋白质还介导细胞之间的直接各种相互作用并调节细胞外环境中发生的过程。细胞因子组蛋白包括淋巴因子、干扰素、集落刺激因子和趋化因子。细胞因子和趋化因子研究对于更深入地了解免疫系统及其对大多数抗原的多方面反应以及疾病状态（例如炎症性疾病，过敏反应，肠易激综合征（IBD），脓毒症和癌症）具有重要作用。

MILLIPLEX®人细胞因子/趋化因子面板4使您能够专注于细胞因子的治疗潜力以及细胞因子表达的调节。

Luminex® xMAP®平台使用磁珠免疫分析格式，以实现理想的速度和灵敏度，同时定量多种分析物，从而显著提高生产力，同时节省宝贵的样本量。

面板类型：细胞因子/趋化因子

特异性

抗体与该面板中任何其他分析物之间的交叉反应性都为无法检测或可忽略。

应用

  • 分析物：BAFF/BLyS，BRAK/CXCL14，CCL28，CXCL16，HCC-4/CCL16，HMGB1，IFNβ，IL-14，IL-19，IL-24，IL-28B，IL-32α，IL-34，IL-35，IL-36β/IL-1F8，IL-37/IL-1F7，IL-38/IL-1F10，MIP-4，MPIF/CCL23，YKL40
  • 推荐的样品类型：血清，血浆和组织/细胞培养上清液
  • 推荐的样品稀释度：1：4稀释的血清或血浆。组织培养上清液可能需要在测定之前用适当的对照培养基稀释
  • 分析运行时间：过夜或2小时初步培养试验。为了获得最佳结果，建议过夜培养。
  • 研究类别：炎症&免疫学
  • 注：HMGB1只能在血清和血浆样品中测量

特点和优势

通过在此面板中选择可用的分析物来设计多重试剂盒。

包装

96孔板

储存及稳定性

试剂盒组分建议的存储温度为2-8°C。

其他说明

请注意：配置此试剂盒时，必须选择样本类型。 HMGB1只能在血清和血浆样品中测量。

法律信息

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

警示用语：

Danger

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

靶器官

Respiratory Tract

WGK

WGK 3

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Carles Perpiñan et al.
Journal of personalized medicine, 12(3) (2022-03-26)
The cytokine signature present in COVID-19 could provide information on the pathogenic mechanisms of the disease and could identify possible prognostic biomarkers and possible therapeutic targets. In this longitudinal work, we studied the clinical and biochemical parameters and circulating cytokine
Hua-Li Sun et al.
BMC infectious diseases, 21(1), 1025-1025 (2021-10-02)
The immunoregulatory functions of regulatory T cells (Tregs) in the development and progression of some chronic infectious diseases are mediated by immune checkpoint molecules and immunosuppressive cytokines. However, little is known about the immunosuppressive functions of Tregs in human brucellosis
Henrik Hill et al.
Biomedicines, 10(1) (2022-01-22)
Gamma-aminobutyric acid (GABA) is an important inhibitory neurotransmitter in the central nervous system (CNS) and outside of the CNS, found in the highest concentrations in immune cells and pancreatic beta-cells. GABA is gaining increasing interest in diabetes research due to

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