跳转至内容
Merck
CN
所有图片(2)

文件

安全信息

HCMBMAG-22K

Millipore

MILLIPLEX® 人癌症/转移生物标志物磁珠板 - 癌症多重检测

Circulating Cancer and Metastasis Biomarker Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple oncology biomarkers in various tumor types in human serum, plasma and cell culture samples.

登录查看公司和协议定价

UNSPSC代码:
12161503
eCl@ss:
32161000
NACRES:
NA.84

质量水平

种属反应性

human

制造商/商品名称

Milliplex®

assay range

accuracy: 70-105%
standard curve range: 0,019-80 ng/mL
(TRAP5)

standard curve range: 0,048-20 ng/mL
(YKL40)

standard curve range: 0.002-10 ng/mL
(GDF15)

standard curve range: 0.007-30 ng/mL
(DKK-1)

standard curve range: 0.007-30 ng/mL
(OPG)

standard curve range: 0.036-150 ng/mL
(NSE)

standard curve range: 0.195-800 ng/mL
(Periostin)

standard curve range: 0.976-4,00 0 ng/mL
(Osteonectin (SPARC))

inter-assay cv: <16%
intra-assay cv: <10%

技术

multiplexing: suitable

检测方法

fluorometric (Luminex xMAP)

运输

wet ice

一般描述

MILLIPLEX®人类癌症/转移生物标记物面板1包含九种转移生物标志物,这些标志物也已在多种肿瘤类型中得到鉴定。结合珠格式的Luminex® xMAP®平台,该面板使研究人员能够专注于发现,并具有同时定量多重检测的优势,从而提高了速度和灵敏度。

转移是一个复杂的过程,其中肿瘤细胞离开原发肿瘤部位,并通过血液和淋巴管或肿瘤侵袭周围组织和器官而迁移到身体的其他部位。脱离原发肿瘤,癌症细胞附着并降解细胞外基质蛋白,这些蛋白将肿瘤与周围组织分开以逃逸到基质中。转移形成的部位通常取决于原发肿瘤。例如,骨转移往往是由乳腺、前列腺和肾脏肿瘤引起的。这种器官/组织特异性似乎涉及来自趋化因子和生长因子的化学信号。

面板类型:循环癌症

应用

  • 分析物:DKK-1、GDF-15、神经元特异性烯醇化酶(NSE)、骨粘连蛋白(SPARC)、骨保护素(OPG)、骨膜素、TRAP5、TWEAK、YKL40(CHI3L1)
  • 推荐样品类型:人血清、血浆和组织/细胞培养上清液或裂解液
  • 推荐的样品稀释度:25 μL 1:10稀释的血清或血浆;稀释的组织/细胞培养上清液或裂解物可根据需要在适当的对照培养基中稀释
  • 分析运行时间:在2-8℃下过夜(16-18小时)
  • 研究类别:癌症

特点和优势

通过在此面板中选择可用的分析物来设计多重试剂盒。

其他说明

灵敏度:有关单个生物标记物的灵敏度,请参阅试剂盒方案。

法律信息

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

警示用语:

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

靶器官

Respiratory Tract

WGK

WGK 3

法规信息

新产品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Paul G Corn et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 26(5), 990-999 (2020-01-17)
Cabozantinib, an oral inhibitor of c-MET/VEGFR2 signaling, improved progression-free survival (mPFS) but not overall survival (OS) in metastatic castrate-resistant prostate cancer. We evaluated cabozantinib plus androgen deprivation therapy (ADT) in hormone-naïve metastatic prostate cancer (HNMPCa). Patients received ADT plus cabozantinib
R H Brophy et al.
Osteoarthritis and cartilage, 27(12), 1778-1789 (2019-08-21)
Emerging evidence suggests that injury to the anterior cruciate ligament (ACL) typically initiates biological changes that contribute to the development of osteoarthritis (OA). The molecular biomarkers or mediators of these biological events remain unknown. The goal of this exploratory study
Alison Crichton et al.
Journal of neurotrauma, 38(8), 1151-1163 (2019-12-28)
Despite many children experiencing fatigue after childhood brain injury, little is known about the predictors of this complaint. To date, traditional indices of traumatic brain injury (TBI) severity have not predicted reliably persisting fatigue (up to three years post-injury). This

相关内容

Multiplex cancer assays accelerate research in cancer biomarkers and tumorigenesis studies.

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门