HBNMAG-51K

MILLIPLEX^® 人骨磁珠板 - 骨代谢多重检测

Name: MILLIPLEX<SUP>®</SUP> 人骨磁珠板 - 骨代谢多重检测
Brand: MM

Configurable Human Bone 13-Plex Panel

别名:

human bone metabolic biomarkers immunoassay panel, luminex human bone metabolism multiplex assay, millipore human bone metabolic biomarkers multiplex kit

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关于此项目

UNSPSC Code:

12161503

NACRES:

NA.84

eCl@ss:

32161000

主要文件

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产品名称

MILLIPLEX^® 人骨磁珠板 - 骨代谢多重检测, Configurable Human Bone 13-Plex Panel

species reactivity

human

manufacturer/tradename

Milliplex^®

Quality Level

200

packaging

1 ea of

assay range

accuracy: 82-97%
standard curve range: 0.24-1,000 pg/mL
(TNFα)
standard curve range: 1-3,000 pg/mL
(IL-1β)
standard curve range: 1-6,000 pg/mL
(ACTH & IL-6)
standard curve range: 146-600,000 pg/mL
(OC)
standard curve range: 24-100,000 pg/mL
(SOST)
standard curve range: 37-150,000 pg/mL
(FGF-23)
standard curve range: 49-200,000 pg/mL
(Leptin)
standard curve range: 5-20,000 pg/mL
(DKK-1)
standard curve range: 5-20,000 pg/mL
(PTH)
standard curve range: 61-250,000 pg/mL
(Insulin)
standard curve range: 7-30,000 pg/mL
(OPG)
standard curve range: 98-400,000 pg/mL
(OPN)

technique(s)

multiplexing: suitable

input

serum plasma (cell culture supernatants, tissue/cell extracts)

detection method

fluorometric (Luminex^® xMAP^® technology)

shipped in

wet ice

storage temp.

2-8°C

Biochem/physiol Actions

交叉反应
对于该面板中的分析物，未观察到抗体之间的交叉反应性。

Features and Benefits

通过在此面板中选择可用的分析物来设计多重试剂盒。

General description

骨代谢是由成骨细胞，骨细胞和破骨细胞控制的正在进行的骨沉积和吸收的动态过程。而成骨细胞和骨细胞（被基质包围的成骨细胞）负责骨沉积，而破骨细胞则负责骨吸收。两者都需要维持骨骼结构以及充足的钙供应。为了维持这种代谢平衡，这些细胞依赖于涉及激素和细胞因子的复杂信号传导途径来实现适当的生长和分化速率。骨代谢紊乱可导致骨质疏松症、骨关节炎、类风湿关节炎、慢性肾脏疾病和骨转移等疾病。

MILLIPLEX^®人骨磁珠试剂盒用于同时定量人血浆、血清或组织/细胞裂解物和培养上清液样品中以下分析物的任何或全部：促肾上腺皮质激素（ACTH)，Dickkopf-1（DKK1），IL-6，胰岛素，瘦素，TNFα，骨质疏松蛋白（OPG），骨钙素（OC），骨桥蛋白（OPN），硬化蛋白（SOST），IL-1β，甲状旁腺素（PTH）和FGF-23。该试剂盒采用96孔板，包含冻干标准混合物、两个内部检测质控品，可最多可测定38份样本，重复两次。

Luminex^® xMAP^®平台使用磁珠免疫分析格式，以实现理想的速度和灵敏度，同时定量多种分析物，从而显著提高生产力，同时节省宝贵的样本量。

面板类型：骨

Bone health is regulated by a complex interplay of hormonal, inflammatory, and metabolic signals. This panel—ACTH, DKK1, FGF-23, IL-1β, IL-6, Insulin, Leptin, Osteocalcin (OC), Osteopontin (OPN), Osteoprotegerin (OPG), PTH, Sclerostin (SOST), and TNFα—captures key indicators of bone remodeling, endocrine function, and immune activity. These analytes are valuable for studying osteoporosis, arthritis, and metabolic bone diseases, supporting both translational and clinical research in skeletal biology.

Other Notes

替代：HBN1B-51K

灵敏度：有关单个分析物的灵敏度，请参见试剂盒方案。

Legal Information

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

Application

MILLIPLEX^® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 13 analytes in human serum, plasma, or cell/tissue culture supernatants.Analytes Included: ACTH, DKK1, FGF-23, IL-1β, IL-6, Insulin, Leptin, Osteocalcin (OC), Osteopontin (OPN), Osteoprotegerin (OPG), PTH, Sclerostin (SOST), TNFαAssay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Disclaimer

For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

pictograms

GHS06,GHS08,GHS05,GHS09

signalword

Danger

hcodes

H302 + H332,H311,H317,H318,H373,H411

pcodes

P273 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P314

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

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MILLIPLEX® 人骨磁珠板 - 骨代谢多重检测