HAGP1MAG-12K

MILLIPLEX^® 人血管生成/生长因子磁珠板 - 癌症多重检测

Name: MILLIPLEX<SUP>®</SUP> 人血管生成/生长因子磁珠板 - 癌症多重检测
Brand: MM

Angiogenesie Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple angiogenic biomarkers in human serum, plasma and cell culture samples.

别名:

human oncology growth factor immunoassay panel, luminex human cancer angiogenesis growth factor multiplex assay, millipore human cancer growth factor protein multiplex kit

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关于此项目

UNSPSC Code:

12161503

NACRES:

NA.84

eCl@ss:

32161000

主要文件

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产品名称

MILLIPLEX^® 人血管生成/生长因子磁珠板 - 癌症多重检测, Angiogenesie Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple angiogenic biomarkers in human serum, plasma and cell culture samples.

species reactivity

human

manufacturer/tradename

Milliplex^®

assay range

accuracy: 42-131%
standard curve range: 1.4-1,000 pg/mL
(HB-EGF, IL-8, PLGF)
standard curve range: 13.7-10,000 pg/mL
(Angiopoietin-2, FGF-1, FGF-2, G-CSF, VEGF-A)
standard curve range: 137.2-100,000 pg/mL
(Leptin)
standard curve range: 2.7-2,000 pg/mL
(BMP-9, EGF, Endothelin-1)
standard curve range: 27.4-20,000 pg/mL
(Endoglin, Follistatin, HGF)
standard curve range: 6.9-5,000 pg/mL
(VEGF-C, VEGF-D)

technique(s)

multiplexing: suitable

Quality Level

200

detection method

fluorometric (Luminex^® xMAP^® technology)

shipped in

wet ice

Application

分析物：血管生成素-2、BMP-9、EGF、内皮糖蛋白、内皮素-1、FGF-1（酸性FGF）、FGF-2（碱性FGF）、卵泡抑素、G-CSF、HB-EGF、HGF、IL-8、瘦素、PLGF、VEGF-A、VEGF-C、VEGF-D
推荐的样品类型：人血清、血浆、组织/细胞裂解物或培养上清液
推荐的样品稀释度：每孔25 μL血浆或血清的1：3稀释液；每孔25 μL细胞培养上清液，根据需要用适当的对照培养基稀释
分析运行时间：在2-8℃下过夜（16-18小时）
研究类别：癌症

Biochem/physiol Actions

交叉反应性
抗体与该面板中任何其他分析物之间的交叉反应性都为无法检测或可忽略。

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

Features and Benefits

通过在此面板中选择可用的分析物来设计多重试剂盒。

General description

血管生成是新血管网的发展，是正常生长和发育以及伤口愈合的关键过程，其动态平衡由血管生成因子和抑制剂的精细平衡维持。因此，血管生长不足或过度是许多疾病的基础，包括心血管疾病，糖尿病溃疡，黄斑变性和癌症。血管生成在肿瘤生长和转移中起着重要作用。

MILLIPLEX^®人血管生成/生长因子面板1用于同时定量人血浆、血清样品和组织/细胞裂解物和因子上清液样品中以下17种人血管生成和生长培养生物标志物的任何或全部：血管生成素-2、BMP-9、EGF、内皮糖蛋白、内皮素-1、FGF-1（酸性FGF）、FGF-2（碱性FGF）、卵泡抑素、G-CSF、HB-EGF、HGF、IL-8、瘦素、PLGF、VEGF-A、VEGF-C和VEGF-D。该试剂盒采用96孔板，包含冻干标准混合物、两个内部检测质控品，最多可测量38份样品，一式两份。

Luminex^® xMAP^®平台使用磁珠免疫分析格式，以实现理想的速度和灵敏度，同时定量多种分析物，从而显著提高生产力，同时节省宝贵的样本量。

面板类型：循环癌症

Other Notes

灵敏度：有关单个分析物的灵敏度，请参阅试剂盒方案。

Packaging

单个试剂盒即可满足您的所有需求。

Preparation Note

试剂盒组分建议的存储温度为2-8°C。

Legal Information

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

pictograms

GHS08,GHS05,GHS07,GHS09

signalword

Danger

hcodes

H302 + H312 + H332,H317,H318,H373,H411

pcodes

P273 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P314

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

存储类别

10 - Combustible liquids

wgk

WGK 3

法规信息

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Bone morphogenetic protein-9 suppresses growth of myeloma cells by signaling through ALK2 but is inhibited by endoglin.

O E Olsen et al.

Blood cancer journal, 4, e196-e196 (2014-03-25)

Multiple myeloma is a malignancy of plasma cells predominantly located in the bone marrow. A number of bone morphogenetic proteins (BMPs) induce apoptosis in myeloma cells in vitro, and with this study we add BMP-9 to the list. BMP-9 has

Regulating VEGF signaling in platelet concentrates via specific VEGF sequestering.

David G Belair et al.

Biomaterials science, 4(5), 819-825 (2016-03-25)

Platelets contain an abundance of growth factors that mimic the composition of the wound healing milieu, and platelet-derived VEGF in particular can negatively influence wound healing if unregulated. Here, we sought to capture and regulate the activity of VEGF factor

Non-coding Double-stranded RNA and Antimicrobial Peptide LL-37 Induce Growth Factor Expression from Keratinocytes and Endothelial Cells.

Christopher A Adase et al.

The Journal of biological chemistry, 291(22), 11635-11646 (2016-04-07)

A critical function for skin is that when damaged it must simultaneously identify the nature of the injury, repair barrier function, and limit the intrusion of pathogenic organisms. These needs are carried out through the detection of damage-associated molecular patterns

Plasma vascular endothelial growth factor A and placental growth factor: novel biomarkers of pulmonary hypertension in congenital diaphragmatic hernia.

Neil Patel et al.

American journal of physiology. Lung cellular and molecular physiology, 308(4), L378-L383 (2014-12-07)

Pulmonary hypertension (PH) due to abnormal pulmonary vascular development is an important determinant of illness severity in congenital diaphragmatic hernia (CDH). Vascular endothelial growth factor A (VEGFA) and placental growth factor (PLGF) may be important mediators of pulmonary vascular development

Quantitative analysis of hormones and inflammatory cytokines in Chlamydia trachomatis-infected women with tubal ectopic pregnancy and early intrauterine pregnancy.

Ruijin Shao et al.

Data in brief, 6, 135-142 (2016-02-10)

In this data, non-pregnant women during the menstrual cycle, women with normal intrauterine pregnancy (IUP), and women with tubal ectopic pregnancy (EP) after informed consent were included. The serum levels of 17β-estradiol, progesterone, testosterone, beta-human chorionic gonadotropin, interleukin (IL)-1β, IL-4

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MILLIPLEX^® 人血管生成/生长因子磁珠板 - 癌症多重检测