产品名称
MILLIPLEX® Human Adipokine Panel, Configurable Human Adipokine 8-Plex Panel 2
species reactivity
human
manufacturer/tradename
Milliplex®
Quality Level
packaging
1 ea of
assay range
accuracy: 87%
(IL-8)
accuracy: 91%
(TNFα)
accuracy: 94%
(Insulin)
standard curve range: 0.64-10,000 pg/mL
(IL-8)
standard curve range: 0.64-10,000 pg/mL
(NGF)
standard curve range: 0.64-10,000 pg/mL
(TNF-α)
standard curve range: 0.96-15,000 pg/mL
(IL-6)
standard curve range: 1.3-20,000 pg/mL
(IL-1β)
standard curve range: 1.3-20,000 pg/mL
(MCP-1)
standard curve range: 38-600,000 pg/mL
(Leptin)
standard curve range: 9.6-150,000 pg/mL
(HGF)
standard curve range: 9.6-150,000 pg/mL
(Insulin)
inter-assay cv: <15%
intra-assay cv: <10%
(IL-1β)
inter-assay cv: <15%
intra-assay cv: <10%
(IL-6)
inter-assay cv: <15%
intra-assay cv: <10%
(IL-8)
inter-assay cv: <15%
intra-assay cv: <10%
(Insulin)
inter-assay cv: <15%
intra-assay cv: <10%
(Leptin)
inter-assay cv: <15%
intra-assay cv: <10%
(MCP-1)
inter-assay cv: <15%
intra-assay cv: <10%
(NGF)
inter-assay cv: <20%
intra-assay cv: <10%
(TNFα)
technique(s)
multiplexing: suitable
input
serum plasma
detection method
fluorometric (Luminex® xMAP® technology)
shipped in
wet ice
storage temp.
2-8°C
Application
Download the HADK2MAG-61K xPonentProtocol Template Version 3.1
MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 8 analytes in human serum or plasma samples.Analytes included: IL-1β, IL-6, IL-8/CXCL8, Insulin, Leptin, MCP-1/CCL2, NGF, TNFαAssay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.
Biochem/physiol Actions
Cross Reactivty
Each antibody pair in a panel is highly specific and displays insignificant cross-reactivity to other analytes in the panel.
Each antibody pair in a panel is highly specific and displays insignificant cross-reactivity to other analytes in the panel.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
General description
Previously the role of white adipose tissue was thought to be limited to energy storage and internal organ protection. The discovery of Leptin secretion from Adipocytes in 1994 led to the recognition that white adipose tissue is involved in a variety of metabolic and physiological processes. Adipocytes secrete several hormones called Adipokines with functions that include appetite and energy balance, insulin sensitivity and lipid metabolism.
The MILLIPLEX® Human Adipokine Panel 2 is an 8-plex kit to be used for the simultaneous quantification of any or all of the following analytes in serum or plasma samples: IL-1β, IL-6, IL-8, Insulin, Leptin, MCP-1, NGF and TNF-α. This kit uses a 96-well format, contains a lyophilized standard cocktail, 2 quality controls and can measure up to 38 samples in duplicate.
Panel Type: Metabolism
The MILLIPLEX® Human Adipokine Panel 2 is an 8-plex kit to be used for the simultaneous quantification of any or all of the following analytes in serum or plasma samples: IL-1β, IL-6, IL-8, Insulin, Leptin, MCP-1, NGF and TNF-α. This kit uses a 96-well format, contains a lyophilized standard cocktail, 2 quality controls and can measure up to 38 samples in duplicate.
Panel Type: Metabolism
Adipokines are signaling proteins secreted by adipose tissue that influence inflammation, metabolism, and energy balance. This set of biomarkers—IL-1β, IL-6, IL-8/CXCL8, Insulin, Leptin, MCP-1/CCL2, NGF, and TNFα—captures the interplay between metabolic regulation and immune response. These analytes are associated with insulin sensitivity, appetite control, inflammatory signaling, and neuroimmune interactions, making them highly relevant for research in obesity, type 2 diabetes, cardiovascular disease, and chronic inflammation.
Other Notes
Sensitivity: See kit protocol for individual sensitives.
Packaging
96-well plate
Everything you need in a single kit.
Preparation Note
Recommended storage for kit components is 2 - 8°C.
Legal Information
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
Luminex is a registered trademark of Luminex Corp
xMAP is a registered trademark of Luminex Corp
Features and Benefits
Features:
- Targets key adipokines and cytokines involved in metabolic and inflammatory pathways
- Includes 8 analytes relevant to insulin signaling, immune response, and adipose tissue function
- Multiplex format enables simultaneous detection from minimal sample volume
- Compatible with human serum and plasma samples
- Designed for research in obesity, insulin resistance, inflammation, and metabolic syndrome
- Provides a comprehensive profile of inflammatory and metabolic biomarkers
- Supports investigation of adipose tissue dysfunction and systemic inflammation
- Facilitates evaluation of therapeutic interventions in metabolic and endocrine disorders
- Enables high-throughput analysis with reduced sample and reagent use
- Delivers reproducible, sensitive results for translational and clinical research
signalword
Danger
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
法规信息
新产品
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相关内容
Multiplex immunoassays, such as MILLIPLEX® multiplex metabolic assays, are critical in metabolic syndrome research because they provide a full picture of the different conditions related to it, like diabetes and obesity, as well as save time and sample volume.
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