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Merck
CN
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FCMAB389F

Sigma-Aldrich

Milli-Mark® Anti-Integrin β1-FITC Antibody, activated, clone HUTS-4

clone HUTS-4, Milli-Mark®, from mouse

别名:

Ligand-induced Binding Site, LIBS, CLIBS

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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

mouse

质量水平

偶联物

FITC conjugate

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

HUTS-4, monoclonal

种属反应性

human

制造商/商品名称

Milli-Mark®

技术

flow cytometry: suitable

同位素/亚型

IgG2b

NCBI登记号

UniProt登记号

运输

wet ice

靶向翻译后修饰

unmodified

基因信息

human ... ITGB1(3688)

一般描述

Integrin beta 1, also known as CD29, is a 130 kDa transmembrane glycoprotein that forms noncovalent complexes with various Integrin alpha subunits 1 to 6 (CD49a to CD49f) also known as Very Late Antigens (VLA). CD29 is also called platelet GPIIa. The antigen mediates cellular adhesion and has broad cellular reactivity, but is not expressed by erythrocytes. In normal peripheral blood it is found on a subset of CD4+ and CD8+ T lymphocytes and on a minority of B lymphocytes. The "inducer" subpopulation of CD4+ lymphocytes co-express CD4 and CD29.

应用

Milli-Mark Anti-Integrin β1-FITC Antibody, activated, clone HUTS-4 is an antibody against Integrin β1 for use in FC.

质量

Evaluated by flow cytometry using A431 cells.

目标描述

88 kDa Calculated

其他说明

Unconjugated antibody Cat. No. MAB2079Z is known to react with Rat.

法律信息

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

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WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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J Meller et al.
Journal of thrombosis and haemostasis : JTH, 10(7), 1397-1408 (2012-05-09)
Kindlin-3 is a novel integrin activator in hematopoietic cells, and its deficiency leads to immune problems and severe bleeding, known as leukocyte adhesion deficiency III (LAD-III). Our current understanding of Kindlin-3 function primarily relies on analysis of animal models or
Marleen Leidecker et al.
Microbiology spectrum, 11(3), e0388622-e0388622 (2023-03-31)
Invasion of host cells is an important feature of Staphylococcus aureus. The main internalization pathway involves binding of the bacteria to host cells, e.g., endothelial cells, via a fibronectin (Fn) bridge between S. aureus Fn binding proteins and α5β1-integrin, followed
Dwayne A L Vickers et al.
PloS one, 8(6), e65828-e65828 (2013-06-14)
Adhesion-based microfluidic cell separation has proven to be very useful in applications ranging from cancer diagnostics to tissue engineering. This process involves functionalizing microchannel surfaces with a capture molecule. High specificity and purity capture can be achieved using this method.
Dasom Shin et al.
Nature communications, 15(1), 2789-2789 (2024-03-31)
Proprotein convertase subtilisin/kexin type-9 (PCSK9) binds to and degrades low-density lipoprotein (LDL) receptor, leading to increase of LDL cholesterol in blood. Its blockers have emerged as promising therapeutics for cardiovascular diseases. Here we show that PCSK9 itself directly induces inflammation

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