生物来源
mouse
质量水平
偶联物
FITC conjugate
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
2A10, monoclonal
种属反应性
human
制造商/商品名称
Milli-Mark®
技术
flow cytometry: suitable
同位素/亚型
IgG1κ
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... BMP7(655)
相关类别
一般描述
Bone morphogenetic protein-7 (BMP-7), also known as osteogenic protein-1, is a member of the TGF- superfamily, and is widely expressed during embryonic development. Like other members of the bone morphogenetic protein family, BMP-7 works synergistically with BMP-2 to play a key role in the differentiation of mesenchymal cells into bone and cartilage tissues by actively recruiting stem cells from the surrounding tissue, thereby initiating the bone formation cascade. In adult cells, BMP-7 is predominately expressed in the brain, kidneys, and bladder.
特异性
This monoclonal antibody recognizes BMP-7.
免疫原
Epitope: Unknown
Recombinant full-length BMP-7 protein.
应用
Working Solution | Cells / test | Total Reaction Volume |
---|---|---|
5 μl | 5 x 105 Cells / 95 μl PBS | 100 μl |
10 μl | 1 x 106 Cells / 90 μl PBS | 100 μl |
Detect BMP-7 using this Milli-Mark Anti-BMP-7-FITC Antibody, clone 2A10 validated for use in FC.
Research Category
Stem Cell Research
Stem Cell Research
Research Sub Category
Mesenchymal Stem Cells
Mesenchymal Stem Cells
质量
Evaluated by flow cytometry using HeLa cells.
目标描述
46kDa Observed
外形
Protein G Purified
Purified mouse monoclonal IgG1κ conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA.
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
HeLa cells.
HeLa cells.
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Unconjugated antibody (MAB4350) also reacts against Mouse.
法律信息
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Veronica Veschi et al.
Oncogene, 39(5), 987-1003 (2019-10-09)
Despite intense research and clinical efforts, patients affected by advanced colorectal cancer (CRC) have still a poor prognosis. The discovery of colorectal (CR) cancer stem cell (CSC) as the cell compartment responsible for tumor initiation and propagation may provide new
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