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FCMAB108A4

Sigma-Aldrich

Anti-phospho-SMC1 (Ser957) Antibody, clone 5D11G5 Alexa Fluor™ 488

clone 5D11G5, from mouse, ALEXA FLUOR™ 488

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别名:
CDLS2, DKFZp686L19178, DXS423E, KIAA0178, MGC138332, OTTHUMP00000061876, SB1.8, SMC1, SMC1A, SMC1L1, SMC1alpha, SMCB, Sb1.8, Smcb
UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

mouse

质量水平

100

偶联物

ALEXA FLUOR™ 488

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

5D11G5, monoclonal

种属反应性

human, Xenopus, bovine

技术

flow cytometry: suitable
western blot: suitable

同位素/亚型

IgG1

NCBI登记号

NM_006306

UniProt登记号

Q14683

运输

wet ice

靶向翻译后修饰

phosphorylation (pSer957)

基因信息

human ... SMC1A(8243)

相关类别

一般描述

SMC (structural maintenance of chromosomes) proteins are Involved in chromosome cohesion during cell cycle and in DNA repair. ATM phosphorylates SMC1 on Ser957 and Ser966 both in vitro and in vivo. Phosphorylated SMC1 is part of the complex that functions as a downstream effector in both the ATM/NBS1 branch and the ATR/MSH2 branch of S-phase checkpoint.

特异性

Antibody recognizes SMC1 phosphorylolated at Ser957.
Predicted to cross-react with xenopus and bovine based on sequence homology

免疫原

Epitope: Phosphorylated at and around Ser957
KLH-conjugated, synthetic peptide corresponding to human SMC1 phosphorylated at Ser957

应用

Research Category
Epigenetics & Nuclear Function

Apoptosis & Cancer
Research Sub Category
Cell Cycle, DNA Replication & Repair
This Anti-phospho-SMC1 (Ser957) Antibody, clone 5D11G5 Alexa Fluor 488 is validated for use in WB, FC for the detection of phospho-SMC1 (Ser957).

质量

Evaluated by Flow Cytometry with Hela Cells

目标描述

150kDa Calculated

外形

Protein G Purified
Purified mouse monoclonal IgG1 conjugated to Alexa Flour 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.

储存及稳定性

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 6 months from date of receipt. Protect from light.

分析说明

Control
HeLa Cells

法律信息

ALEXA FLUOR is a trademark of Life Technologies

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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