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Merck
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EZRMGIP

Millipore

Rat/Mouse GIP ELISA Kit

measures and quantifies GIP levels in 10 μL serum, plasma or cell culture supernatent

别名:

Gastric inhibitory polypeptide, Glucose-dependent insulinotropic polypeptide, Incretin hormone

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About This Item

UNSPSC代码:
12161503
eCl@ss:
32161000
NACRES:
NA.32

产品名称

大鼠/小鼠GIP（总）ELISA, This Rat/Mouse GIP (total) ELISA is used to measure & quantify GIP levels in Metabolism & Endocrine research.

质量水平

200

种属反应性

mouse, rat

包装

kit of 1 × 96 wells

参数

10 μL sample volume (4hr assay)

assay range

accuracy: 104.2%
linearity: 100.8%
sensitivity: 8.2 pg/mL
standard curve range: 8.2-2000 pg/mL

技术

ELISA: suitable

输入

sample type cell culture supernatant
sample type plasma (K2 EDTA)
sample type serum

UniProt登记号

P48756
Q06145

应用

research use

相关类别

一般描述

胃抑制肽(GIP)或葡萄糖依赖性胰岛素性多肽是一种胃肠肽激素，属于胰高血糖素超家族。经十二指肠内分泌K细胞吸收葡萄糖或脂肪后释放。GIP参与葡萄糖诱导的胰岛素分泌。该大鼠/小鼠GIP（总计）ELISA用于测量定量代谢和内分泌研究中的GIP水平。

应用

采用大鼠/小鼠总GIP ELISA法测定大鼠血浆和血清中总GIP的含量。

免责声明

仅供研究使用。不用于诊断操作。

警示用语：

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Met. Corr. 1 - Skin Sens. 1

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

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N Inagaki et al.
Molecular endocrinology (Baltimore, Md.), 3(6), 1014-1021 (1989-06-01)
Gastric inhibitory polypeptide (GIP) is a 42-amino-acid hormone which may have a role in the regulation of insulin secretion. The characterization of cDNA clones encoding this hormone indicates that it is derived by proteolytic processing of a 153-amino-acid precursor. The
N-oleoyldopamine enhances glucose homeostasis through the activation of GPR119.
Zhi-Liang Chu,Chris Carroll,Ruoping Chen,Jean Alfonso,Veronica Gutierrez,Hongmei He et al.
Molecular Endocrinology null
K Miyawaki et al.
Proceedings of the National Academy of Sciences of the United States of America, 96(26), 14843-14847 (1999-12-28)
Mice with a targeted mutation of the gastric inhibitory polypeptide (GIP) receptor gene (GIPR) were generated to determine the role of GIP as a mediator of signals from the gut to pancreatic beta cells. GIPR-/- mice have higher blood glucose
Trehalose prevents adipocyte hypertrophy and mitigates insulin resistance.
Chikako Arai,Norie Arai,Akiko Mizote,Keizo Kohno,Kanso Iwaki,Toshiharu Hanaya et al.
Nutrition Research (New York, N.Y.) null
Gpr40 is expressed in enteroendocrine cells and mediates free fatty acid stimulation of incretin secretion.
Sara Edfalk, Par Steneberg, Helena Edlund
Diabetes null
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